Investigating D-Lysine Stereochemistry for Epigenetic Methylation, Demethylation and Recognition

Histone lysine methylation is regulated by N(ε)-methyltransferases, demethylases, and N(ε)-methyl lysine binding proteins. Thermodynamic, catalytic and computational studies were carried out to investigate the interaction of three epigenetic protein classes with synthetic histone substrates containi...

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Publicat a:Chem Commun (Camb)
Autors principals: Belle, Roman, Al Temimi, Abbas H. K., Kumar, Kiran, Pieters, Bas J. G. E., Tumber, Anthony, Dunford, James E., Johansson, Catrine, Oppermann, Udo, Brown, Tom, Schofield, Christopher J., Hopkinson, Richard J., Paton, Robert S., Kawamura, Akane, Mecinović, Jasmin
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345366/
https://ncbi.nlm.nih.gov/pubmed/29186216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7cc08028j
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