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Investigating D-Lysine Stereochemistry for Epigenetic Methylation, Demethylation and Recognition

Histone lysine methylation is regulated by N(ε)-methyltransferases, demethylases, and N(ε)-methyl lysine binding proteins. Thermodynamic, catalytic and computational studies were carried out to investigate the interaction of three epigenetic protein classes with synthetic histone substrates containi...

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Bibliografiska uppgifter
I publikationen:Chem Commun (Camb)
Huvudupphovsmän: Belle, Roman, Al Temimi, Abbas H. K., Kumar, Kiran, Pieters, Bas J. G. E., Tumber, Anthony, Dunford, James E., Johansson, Catrine, Oppermann, Udo, Brown, Tom, Schofield, Christopher J., Hopkinson, Richard J., Paton, Robert S., Kawamura, Akane, Mecinović, Jasmin
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345366/
https://ncbi.nlm.nih.gov/pubmed/29186216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7cc08028j
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