Investigating D-Lysine Stereochemistry for Epigenetic Methylation, Demethylation and Recognition

Histone lysine methylation is regulated by N(ε)-methyltransferases, demethylases, and N(ε)-methyl lysine binding proteins. Thermodynamic, catalytic and computational studies were carried out to investigate the interaction of three epigenetic protein classes with synthetic histone substrates containi...

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Bibliografske podrobnosti
izdano v:Chem Commun (Camb)
Main Authors: Belle, Roman, Al Temimi, Abbas H. K., Kumar, Kiran, Pieters, Bas J. G. E., Tumber, Anthony, Dunford, James E., Johansson, Catrine, Oppermann, Udo, Brown, Tom, Schofield, Christopher J., Hopkinson, Richard J., Paton, Robert S., Kawamura, Akane, Mecinović, Jasmin
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345366/
https://ncbi.nlm.nih.gov/pubmed/29186216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7cc08028j
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