Investigating D-Lysine Stereochemistry for Epigenetic Methylation, Demethylation and Recognition

Histone lysine methylation is regulated by N(ε)-methyltransferases, demethylases, and N(ε)-methyl lysine binding proteins. Thermodynamic, catalytic and computational studies were carried out to investigate the interaction of three epigenetic protein classes with synthetic histone substrates containi...

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Detalhes bibliográficos
Publicado no:Chem Commun (Camb)
Main Authors: Belle, Roman, Al Temimi, Abbas H. K., Kumar, Kiran, Pieters, Bas J. G. E., Tumber, Anthony, Dunford, James E., Johansson, Catrine, Oppermann, Udo, Brown, Tom, Schofield, Christopher J., Hopkinson, Richard J., Paton, Robert S., Kawamura, Akane, Mecinović, Jasmin
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345366/
https://ncbi.nlm.nih.gov/pubmed/29186216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7cc08028j
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