Human SNM1A and XPF–ERCC1 collaborate to initiate DNA interstrand cross-link repair

One of the major DNA interstrand cross-link (ICL) repair pathways in mammalian cells is coupled to replication, but the mechanistic roles of the critical factors involved remain largely elusive. Here, we show that purified human SNM1A (hSNM1A), which exhibits a 5′–3′ exonuclease activity, can load f...

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Hauptverfasser: Wang, Anderson T., Sengerová, Blanka, Cattell, Emma, Inagawa, Takabumi, Hartley, Janet M., Kiakos, Konstantinos, Burgess-Brown, Nicola A., Swift, Lonnie P., Enzlin, Jacqueline H., Schofield, Christopher J., Gileadi, Opher, Hartley, John A., McHugh, Peter J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2011
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175721/
https://ncbi.nlm.nih.gov/pubmed/21896658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.15699211
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