Pharmacological Targeting of the Hsp70 Chaperone

Yazar: Patury, Srikanth, Miyata, Yoshinari, Gestwicki, Jason E.
Baskı/Yayın Bilgisi 2009

Molecular chaperones and regulation of tau quality control: strategies for drug discovery in tauopathies

Yazar: Miyata, Yoshinari, Koren, John, Kiray, Janine, Dickey, Chad A, Gestwicki, Jason E
Baskı/Yayın Bilgisi 2011

Safety and Efficacy of Avaren-Fc Lectibody Targeting HCV High-Mannose Glycans in a Human Liver Chimeric Mouse Model

Yazar: Dent, Matthew, Hamorsky, Krystal, Vausselin, Thibaut, Dubuisson, Jean, Miyata, Yoshinari, Morikawa, Yoshio, Matoba, Nobuyuki
Yayımlandı Cell Mol Gastroenterol Hepatol (2020)

HEME-DEPENDENT ACTIVATION OF NEURONAL NITRIC-OXIDE SYNTHASE BY CYTOSOL IS DUE TO AN HSP70-DEPENDENT, THIOREDOXIN-MEDIATED THIOL-DISULFIDE INTERCHANGE IN THE HEME/SUBSTRATE BINDING...

Yazar: Morishima, Yoshihiro, Lau, Miranda, Peng, Hwei-Ming, Miyata, Yoshinari, Gestwicki, Jason E., Pratt, William B., Osawa, Yoichi
Baskı/Yayın Bilgisi 2011

Cysteine Reactivity Distinguishes Redox Sensing by the Heat Inducible and Constitutive Forms of Heat Shock Protein 70 (Hsp70)

Yazar: Miyata, Yoshinari, Rauch, Jennifer N., Jinwal, Umesh K., Thompson, Andrea D., Srinivasan, Sharan, Dickey, Chad A., Gestwicki, Jason E.
Baskı/Yayın Bilgisi 2012

High Throughput Screen for Escherichia coli Heat Shock Protein 70 (Hsp70/DnaK): ATPase Assay in Low Volume By Exploiting Energy Transfer

Yazar: Miyata, Yoshinari, Chang, Lyra, Bainor, Anthony, McQuade, Thomas J., Walczak, Christopher P., Zhang, Yaru, Larsen, Martha J., Kirchhoff, Paul, Gestwicki, Jason E.
Baskı/Yayın Bilgisi 2010

A Screen for Modulators of Large T Antigen's ATPase Activity Uncovers Novel Inhibitors of Simian Virus 40 and BK Virus Replication

Yazar: Seguin, Sandlin P., Ireland, Alex W., Gupta, Tushar, Wright, Christine M., Miyata, Yoshinari, Wipf, Peter, Pipas, James M., Gestwicki, Jason E., Brodsky, Jeffrey L.
Baskı/Yayın Bilgisi 2012

Chemical Screens Against A Reconstituted Multi-Protein Complex: Myricetin Blocks DnaJ Regulation of DnaK through an Allosteric Mechanism

Yazar: Chang, Lyra, Miyata, Yoshinari, Ung, Peter M. U., Bertelsen, Eric B., McQuade, Thomas J., Carlson, Heather A., Zuiderweg, Erik R. P., Gestwicki, Jason E.
Baskı/Yayın Bilgisi 2011

Synthesis and Initial Evaluation of YM-08, a Blood-Brain Barrier Permeable Derivative of the Heat Shock Protein 70 (Hsp70) Inhibitor MKT-077, Which Reduces Tau Levels

Yazar: Miyata, Yoshinari, Li, Xiaokai, Lee, Hsiu-Fang, Jinwal, Umesh K., Srinivasan, Sharan R., Seguin, Sandlin P., Young, Zapporah T., Brodsky, Jeffrey L., Dickey, Chad A., Sun, Duxin, Gestwicki, Jason E.
Baskı/Yayın Bilgisi 2013

Rhodacyanine Derivative Selectively Targets Cancer Cells and Overcomes Tamoxifen Resistance

Yazar: Koren, John, Miyata, Yoshinari, Kiray, Janine, O'Leary, John C., Nguyen, Lana, Guo, Jianping, Blair, Laura J., Li, Xiokai, Jinwal, Umesh K., Cheng, Jin Q., Gestwicki, Jason E., Dickey, Chad A.
Baskı/Yayın Bilgisi 2012

Correction: Rhodacyanine Derivative Selectively Targets Cancer Cells and Overcomes Tamoxifen Resistance

Yazar: Koren, John, Miyata, Yoshinari, Kiray, Janine, O'Leary, John C., Nguyen, Lana, Guo, Jianping, Blair, Laura J., Li, Xiaokai, Jinwal, Umesh K., Cheng, Jin Q., Gestwicki, Jason E., Dickey, Chad A.
Baskı/Yayın Bilgisi 2012

Intradiscal injection of simvastatin results in radiologic, histologic, and genetic evidence of disc regeneration in a rat model of degenerative disc disease

Yazar: Than, Khoi D., Rahman, Shayan U., Wang, Lin, Khan, Adam, Kyere, Kwaku A., Than, Tracey T., Miyata, Yoshinari, Park, Yoon-Shin, La Marca, Frank, Kim, Hyungjin M., Zhang, Huina, Park, Paul, Lin, Chia-Ying
Baskı/Yayın Bilgisi 2013

Activation of Hsp70 reduces neurotoxicity by promoting polyglutamine protein degradation

Yazar: Wang, Adrienne M., Miyata, Yoshinari, Klinedinst, Susan, Peng, Hwei-Ming, Chua, Jason P., Komiyama, Tomoko, Li, Xiaokai, Morishima, Yoshihiro, Merry, Diane E., Pratt, William B., Osawa, Yoichi, Collins, Catherine A., Gestwicki, Jason E., Lieberman, Andrew P.
Baskı/Yayın Bilgisi 2012

Chemical Manipulation of Hsp70 ATPase Activity Regulates Tau Stability

Yazar: Jinwal, Umesh K., Miyata, Yoshinari, Koren, John, Jones, Jeffrey R., Trotter, Justin H., Chang, Lyra, O'Leary, John, Morgan, David, Lee, Daniel C., Shults, Cody L., Rousaki, Aikaterini, Weeber, Edwin J., Zuiderweg, Erik R. P., Gestwicki, Jason E., Dickey, Chad A.
Baskı/Yayın Bilgisi 2009

Facilitating Akt Clearance via Manipulation of Hsp70 Activity and Levels

Yazar: Koren, John, Jinwal, Umesh K., Jin, Ying, O'Leary, John, Jones, Jeff R., Johnson, Amelia G., Blair, Laura J., Abisambra, Jose F., Chang, Lyra, Miyata, Yoshinari, Cheng, Anna M., Guo, Jianping, Cheng, Jin Q., Gestwicki, Jason E., Dickey, Chad A.
Baskı/Yayın Bilgisi 2010

Hsc70 Rapidly Engages Tau after Microtubule Destabilization

Yazar: Jinwal, Umesh K., O'Leary, John C., Borysov, Sergiy I., Jones, Jeffrey R., Li, Qingyou, Koren, John, Abisambra, Jose F., Vestal, Grant D., Lawson, Lisa Y., Johnson, Amelia G., Blair, Laura J., Jin, Ying, Miyata, Yoshinari, Gestwicki, Jason E., Dickey, Chad A.
Baskı/Yayın Bilgisi 2010

Allosteric heat shock protein 70 inhibitors rapidly rescue synaptic plasticity deficits by reducing aberrant tau

Yazar: Abisambra, Jose, Jinwal, Umesh K., Miyata, Yoshinari, Rogers, Justin, Blair, Laura, Li, Xiaokai, Seguin, Sandlin P., Wang, Li, Jin, Ying, Bacon, Justin, Brady, Sarah, Cockman, Matthew, Guidi, Chantal, Zhang, Juan, Koren, John, Young, Zapporah T., Atkins, Christopher A., Zhang, Bo, Lawson, Lisa Y., Weeber, Edwin J., Brodsky, Jeffrey L., Gestwicki, Jason E., Dickey, Chad A.
Baskı/Yayın Bilgisi 2013