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A Screen for Modulators of Large T Antigen's ATPase Activity Uncovers Novel Inhibitors of Simian Virus 40 and BK Virus Replication

New polyomaviruses are continually being identified, and it is likely that links between this virus family and disease will continue to emerge. Unfortunately, a specific treatment for polyomavirus-associated disease is lacking. Because polyomaviruses express large Tumor Antigen, TAg, we hypothesized...

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Detalhes bibliográficos
Main Authors: Seguin, Sandlin P., Ireland, Alex W., Gupta, Tushar, Wright, Christine M., Miyata, Yoshinari, Wipf, Peter, Pipas, James M., Gestwicki, Jason E., Brodsky, Jeffrey L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465505/
https://ncbi.nlm.nih.gov/pubmed/22898086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2012.07.012
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