Development of Class IIa Bacteriocins as Therapeutic Agents

le Lohans, Christopher T., Vederas, John C.
Foilsithe 2012

New Delhi Metallo-β-Lactamase 1 Catalyzes Avibactam and Aztreonam Hydrolysis

le Lohans, Christopher T., Brem, Jürgen, Schofield, Christopher J.
Foilsithe in Antimicrob Agents Chemother (2017)

Draft Genome Sequences of Paenibacillus polymyxa NRRL B-30509 and Paenibacillus terrae NRRL B-30644, Strains from a Poultry Environment That Produce Tridecaptin A and Paenicidins

le van Belkum, Marco J., Lohans, Christopher T., Vederas, John C.
Foilsithe in Genome Announc (2015)

Roles of 2-oxoglutarate oxygenases and isopenicillin N synthase in β-lactam biosynthesis

le Rabe, Patrick, Kamps, Jos J. A. G., Schofield, Christopher J., Lohans, Christopher T.
Foilsithe in Nat Prod Rep (2018)

Analysis of β-lactone formation by clinically observed carbapenemases informs on a novel antibiotic resistance mechanism

le Aertker, Kristina M.J., Chan, H.T. Henry, Lohans, Christopher T., Schofield, Christopher J.
Foilsithe in J Biol Chem (2021)

A Fluorescence‐Based Assay for Screening β‐Lactams Targeting the Mycobacterium tuberculosis Transpeptidase Ldt(Mt2)

le de Munnik, Mariska, Lohans, Christopher T., Langley, Gareth W., Bon, Corentin, Brem, Jürgen, Schofield, Christopher J.
Foilsithe in Chembiochem (2019)

Genetic Determinants of Reutericyclin Biosynthesis in Lactobacillus reuteri

le Lin, Xiaoxi B., Lohans, Christopher T., Duar, Rebbeca, Zheng, Jinshui, Vederas, John C., Walter, Jens, Gänzle, Michael
Foilsithe in Appl Environ Microbiol (2015)

Solution Structure of Acidocin B, a Circular Bacteriocin Produced by Lactobacillus acidophilus M46

le Acedo, Jeella Z., van Belkum, Marco J., Lohans, Christopher T., McKay, Ryan T., Miskolzie, Mark, Vederas, John C.
Foilsithe in Appl Environ Microbiol (2015)

(19)F NMR Monitoring of Reversible Protein Post‐Translational Modifications: Class D β‐Lactamase Carbamylation and Inhibition

le van Groesen, Emma, Lohans, Christopher T., Brem, Jürgen, Aertker, Kristina M. J., Claridge, Timothy D. W., Schofield, Christopher J.
Foilsithe in Chemistry (2019)

A New Mechanism for β‐Lactamases: Class D Enzymes Degrade 1β‐Methyl Carbapenems through Lactone Formation

le Lohans, Christopher T., van Groesen, Emma, Kumar, Kiran, Tooke, Catherine L., Spencer, James, Paton, Robert S., Brem, Jürgen, Schofield, Christopher J.
Foilsithe in Angew Chem Int Ed Engl (2018)

Mechanistic Insights into β-Lactamase-Catalysed Carbapenem Degradation Through Product Characterisation

le Lohans, Christopher T., Freeman, Emily I., Groesen, Emma van, Tooke, Catherine L., Hinchliffe, Philip, Spencer, James, Brem, Jürgen, Schofield, Christopher J.
Foilsithe in Sci Rep (2019)

Expansion of base excision repair compensates for a lack of DNA repair by oxidative dealkylation in budding yeast

le Admiraal, Suzanne J., Eyler, Daniel E., Baldwin, Michael R., Brines, Emily M., Lohans, Christopher T., Schofield, Christopher J., O'Brien, Patrick J.
Foilsithe in J Biol Chem (2019)

Targeting the Mycobacterium tuberculosis transpeptidase Ldt(Mt2) with cysteine-reactive inhibitors including ebselen

le de Munnik, Mariska, Lohans, Christopher T., Lang, Pauline A., Langley, Gareth W., Malla, Tika R., Tumber, Anthony, Schofield, Christopher J., Brem, Jürgen
Foilsithe in Chem Commun (Camb) (2019)

Draft Genome Sequence of the Bacteriocin-Producing Strain Enterococcus faecium M3K31, Isolated from Griffon Vultures (Gyps fulvus subsp. fulvus)

le Arbulu, Sara, Frantzen, Cyril, Lohans, Christopher T., Cintas, Luis M., Herranz, Carmen, Holo, Helge, Diep, Dzung B., Vederas, John C., Hernández, Pablo E.
Foilsithe in Genome Announc (2016)

Structural and stereoelectronic insights into oxygenase-catalyzed formation of ethylene from 2-oxoglutarate

le Zhang, Zhihong, Smart, Tristan J., Choi, Hwanho, Hardy, Florence, Lohans, Christopher T., Abboud, Martine I., Richardson, Melodie S. W., Paton, Robert S., McDonough, Michael A., Schofield, Christopher J.
Foilsithe in Proc Natl Acad Sci U S A (2017)

NMR-filtered virtual screening leads to non-metal chelating metallo-β-lactamase inhibitors

le Li, Guo-Bo, Abboud, Martine I., Brem, Jürgen, Someya, Hidenori, Lohans, Christopher T., Yang, Sheng-Yong, Spencer, James, Wareham, David W., McDonough, Michael A., Schofield, Christopher J.
Foilsithe in Chem Sci (2017)

Structure-Based in Silico Screening Identifies a Potent Ebolavirus Inhibitor from a Traditional Chinese Medicine Library

le Shaikh, Faraz, Zhao, Yuguang, Alvarez, Luis, Iliopoulou, Maria, Lohans, Christopher, Schofield, Christopher J., Padilla-Parra, Sergi, Siu, Shirley W. I., Fry, Elizabeth E., Ren, Jingshan, Stuart, David I.
Foilsithe in J Med Chem (2019)

Selective Inhibitors of a Human Prolyl Hydroxylase (OGFOD1) Involved in Ribosomal Decoding

le Thinnes, Cyrille C., Lohans, Christopher T., Abboud, Martine I., Yeh, Tzu‐Lan, Tumber, Anthony, Nowak, Radosław P., Attwood, Martin, Cockman, Matthew E., Oppermann, Udo, Loenarz, Christoph, Schofield, Christopher J.
Foilsithe in Chemistry (2019)

Correction to “Structure-Based in Silico Screening Identifies a Potent Ebolavirus Inhibitor from a Traditional Chinese Medicine Library”

le Shaikh, Faraz, Zhao, Yuguang, Alvarez, Luis, Iliopoulou, Maria, Lohans, Christopher, Schofield, Christopher J., Padilla-Parra, Sergi, Siu, Shirley W. I., Fry, Elizabeth E., Ren, Jingshan, Stuart, David I.
Foilsithe in J Med Chem (2019)

Biochemical and biophysical analyses of hypoxia sensing prolyl hydroxylases from Dictyostelium discoideum and Toxoplasma gondii

le Liu, Tongri, Abboud, Martine I., Chowdhury, Rasheduzzaman, Tumber, Anthony, Hardy, Adam P., Lippl, Kerstin, Lohans, Christopher T., Pires, Elisabete, Wickens, James, McDonough, Michael A., West, Christopher M., Schofield, Christopher J.
Foilsithe in J Biol Chem (2021)