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Roles of 2-oxoglutarate oxygenases and isopenicillin N synthase in β-lactam biosynthesis
Covering: up to 2017 2-Oxoglutarate (2OG) dependent oxygenases and the homologous oxidase isopenicillin N synthase (IPNS) play crucial roles in the biosynthesis of β-lactam ring containing natural products. IPNS catalyses formation of the bicyclic penicillin nucleus from a tripeptide. 2OG oxygenases...
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| Publicado no: | Nat Prod Rep |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6097109/ https://ncbi.nlm.nih.gov/pubmed/29808887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8np00002f |
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