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Protein Hydroxylation Catalyzed by 2-Oxoglutarate-dependent Oxygenases

The post-translational hydroxylation of prolyl and lysyl residues, as catalyzed by 2-oxoglutarate (2OG)-dependent oxygenases, was first identified in collagen biosynthesis. 2OG oxygenases also catalyze prolyl and asparaginyl hydroxylation of the hypoxia-inducible factors that play important roles in...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Principais autores: Markolovic, Suzana, Wilkins, Sarah E., Schofield, Christopher J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4543633/
https://ncbi.nlm.nih.gov/pubmed/26152730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R115.662627
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