Target Identification and Mode of Action of Four Chemically Divergent Drugs against Ebolavirus Infection

Por Ren, Jingshan, Zhao, Yuguang, Fry, Elizabeth E., Stuart, David I.
Publicado no J Med Chem (2017)

Hepatitis A Virus Capsid Structure

Por Stuart, David I., Ren, Jingshan, Wang, Xiangxi, Rao, Zihe, Fry, Elizabeth E.
Publicado no Cold Spring Harb Perspect Med (2019)

Lysosome sorting of β-glucocerebrosidase by LIMP-2 is targeted by the mannose 6-phosphate receptor

Por Zhao, Yuguang, Ren, Jingshan, Padilla-Parra, Sergi, Fry, Elizabeth E., Stuart, David I.
Publicado em 2014

Glutathione facilitates enterovirus assembly by binding at a druggable pocket

Por Duyvesteyn, Helen M. E., Ren, Jingshan, Walter, Thomas S., Fry, Elizabeth E., Stuart, David I.
Publicado no Commun Biol (2020)

Specificity of the VP1 GH Loop of Foot-and-Mouth Disease Virus for αv Integrins

Por Burman, Alison, Clark, Stuart, Abrescia, Nicola G. A., Fry, Elizabeth E., Stuart, David I., Jackson, Terry
Publicado em 2006

A plate-based high-throughput assay for virus stability and vaccine formulation

Por Walter, Thomas S., Ren, Jingshan, Tuthill, Tobias J., Rowlands, David J., Stuart, David I., Fry, Elizabeth E.
Publicado em 2012

Mammalian expression of virus-like particles as a proof of principle for next generation polio vaccines

Por Bahar, Mohammad W., Porta, Claudine, Fox, Helen, Macadam, Andrew J., Fry, Elizabeth E., Stuart, David I.
Publicado no NPJ Vaccines (2021)

Evaluation and Use of In-Silico Structure-Based Epitope Prediction with Foot-and-Mouth Disease Virus

Por Borley, Daryl W., Mahapatra, Mana, Paton, David J., Esnouf, Robert M., Stuart, David I., Fry, Elizabeth E.
Publicado em 2013

Potent antiviral agents fail to elicit genetically-stable resistance mutations in either enterovirus 71 or Coxsackievirus A16

Por Kelly, James T., De Colibus, Luigi, Elliott, Lauren, Fry, Elizabeth E., Stuart, David I., Rowlands, David J., Stonehouse, Nicola J.
Publicado no Antiviral Res (2015)

SAT2 Foot-and-Mouth Disease Virus Structurally Modified for Increased Thermostability

Por Scott, Katherine A., Kotecha, Abhay, Seago, Julian, Ren, Jingshan, Fry, Elizabeth E., Stuart, David I., Charleston, Bryan, Maree, Francois F.
Publicado no J Virol (2017)

Crystal Structure of Swine Vesicular Disease Virus and Implications for Host Adaptation

Por Fry, Elizabeth E., Knowles, Nick J., Newman, John W. I., Wilsden, Ginette, Rao, Zihe, King, Andrew M. Q., Stuart, David I.
Publicado em 2003

Equine Rhinitis A Virus and Its Low pH Empty Particle: Clues Towards an Aphthovirus Entry Mechanism?

Por Tuthill, Tobias J., Harlos, Karl, Walter, Thomas S., Knowles, Nick J., Groppelli, Elisabetta, Rowlands, David J., Stuart, David I., Fry, Elizabeth E.
Publicado em 2009

Structures of foot and mouth disease virus pentamers: Insight into capsid dissociation and unexpected pentamer reassociation

Por Malik, Nayab, Kotecha, Abhay, Gold, Sarah, Asfor, Amin, Ren, Jingshan, Huiskonen, Juha T., Tuthill, Tobias J., Fry, Elizabeth E., Stuart, David I.
Publicado no PLoS Pathog (2017)

Exploiting fast detectors to enter a new dimension in room-temperature crystallography

Por Owen, Robin L., Paterson, Neil, Axford, Danny, Aishima, Jun, Schulze-Briese, Clemens, Ren, Jingshan, Fry, Elizabeth E., Stuart, David I., Evans, Gwyndaf
Publicado em 2014

Rational Engineering of Recombinant Picornavirus Capsids to Produce Safe, Protective Vaccine Antigen

Por Porta, Claudine, Kotecha, Abhay, Burman, Alison, Jackson, Terry, Ren, Jingshan, Loureiro, Silvia, Jones, Ian M., Fry, Elizabeth E., Stuart, David I., Charleston, Bryan
Publicado em 2013

Toremifene interacts with and destabilizes the Ebola virus glycoprotein

Por Zhao, Yuguang, Ren, Jingshan, Harlos, Karl, Jones, Daniel M., Zeltina, Antra, Bowden, Thomas A., Padilla-Parra, Sergi, Fry, Elizabeth E., Stuart, David I.
Publicado no Nature (2016)

Plant-made polio type 3 stabilized VLPs—a candidate synthetic polio vaccine

Por Marsian, Johanna, Fox, Helen, Bahar, Mohammad W., Kotecha, Abhay, Fry, Elizabeth E., Stuart, David I., Macadam, Andrew J., Rowlands, David J., Lomonossoff, George P.
Publicado no Nat Commun (2017)

Neutralization Mechanisms of Two Highly Potent Antibodies against Human Enterovirus 71

Por Zhu, Ling, Xu, Kangwei, Wang, Nan, Cao, Lei, Wu, Junlan, Gao, Qiang, Fry, Elizabeth E., Stuart, David I., Rao, Zihe, Wang, Junzhi, Wang, Xiangxi
Publicado no mBio (2018)

Hand-foot-and-mouth disease virus receptor KREMEN1 binds the canyon of Coxsackie Virus A10

Por Zhao, Yuguang, Zhou, Daming, Ni, Tao, Karia, Dimple, Kotecha, Abhay, Wang, Xiangxi, Rao, Zihe, Jones, E. Yvonne, Fry, Elizabeth E., Ren, Jingshan, Stuart, David I.
Publicado no Nat Commun (2020)

Symmetrical arrangement of positively charged residues around the 5-fold axes of SAT type foot-and-mouth disease virus enhances cell culture of field viruses

Por Chitray, Melanie, Kotecha, Abhay, Nsamba, Peninah, Ren, Jingshan, Maree, Sonja, Ramulongo, Tovhowani, Paul, Guntram, Theron, Jacques, Fry, Elizabeth E., Stuart, David I., Maree, Francois F.
Publicado no PLoS Pathog (2020)