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Specificity of the VP1 GH Loop of Foot-and-Mouth Disease Virus for αv Integrins

Foot-and-mouth disease virus (FMDV) can use a number of integrins as receptors to initiate infection. Attachment to the integrin is mediated by a highly conserved arginine-glycine-aspartic acid (RGD) tripeptide located on the GH loop of VP1. Other residues of this loop are also conserved and may con...

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Detalhes bibliográficos
Main Authors: Burman, Alison, Clark, Stuart, Abrescia, Nicola G. A., Fry, Elizabeth E., Stuart, David I., Jackson, Terry
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1617245/
https://ncbi.nlm.nih.gov/pubmed/16973584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00577-06
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