Inherent DNA‐binding specificities of the HIF‐1α and HIF‐2α transcription factors in chromatin

Hypoxia‐inducible factor (HIF) is the major transcriptional regulator of cellular responses to hypoxia. The two principal HIF‐α isoforms, HIF‐1α and HIF‐2α, are progressively stabilized in response to hypoxia and form heterodimers with HIF‐1β to activate a broad range of transcriptional responses. H...

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Detaylı Bibliyografya
Yayımlandı:EMBO Rep
Asıl Yazarlar: Smythies, James A, Sun, Min, Masson, Norma, Salama, Rafik, Simpson, Peter D, Murray, Elizabeth, Neumann, Viviana, Cockman, Matthew E, Choudhry, Hani, Ratcliffe, Peter J, Mole, David R
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2018
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322389/
https://ncbi.nlm.nih.gov/pubmed/30429208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201846401
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