Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts

Hypoxia-inducible factor (HIF) controls an extensive range of adaptive responses to hypoxia. To better understand this transcriptional cascade we performed genome-wide chromatin immunoprecipitation using antibodies to two major HIF-α subunits, and correlated the results with genome-wide transcript p...

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Detalhes bibliográficos
Main Authors: Mole, David R., Blancher, Christine, Copley, Richard R., Pollard, Patrick J., Gleadle, Jonathan M., Ragoussis, Jiannis, Ratcliffe, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Transcription, Chromatin, and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719312/
https://ncbi.nlm.nih.gov/pubmed/19386601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M901790200
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