Proteomics-based Identification of Novel Factor Inhibiting Hypoxia-inducible Factor (FIH) Substrates Indicates Widespread Asparaginyl Hydroxylation of Ankyrin Repeat Domain-contain...

Por Cockman, Matthew E., Webb, James D., Kramer, Holger B., Kessler, Benedikt M., Ratcliffe, Peter J.
Publicado em 2009

Quantitative Mass Spectrometry Reveals Dynamics of Factor-inhibiting Hypoxia-inducible Factor-catalyzed Hydroxylation

Por Singleton, Rachelle S., Trudgian, David C., Fischer, Roman, Kessler, Benedikt M., Ratcliffe, Peter J., Cockman, Matthew E.
Publicado em 2011

Inherent DNA‐binding specificities of the HIF‐1α and HIF‐2α transcription factors in chromatin

Por Smythies, James A, Sun, Min, Masson, Norma, Salama, Rafik, Simpson, Peter D, Murray, Elizabeth, Neumann, Viviana, Cockman, Matthew E, Choudhry, Hani, Ratcliffe, Peter J, Mole, David R
Publicado no EMBO Rep (2018)

Selective Inhibitors of a Human Prolyl Hydroxylase (OGFOD1) Involved in Ribosomal Decoding

Por Thinnes, Cyrille C., Lohans, Christopher T., Abboud, Martine I., Yeh, Tzu‐Lan, Tumber, Anthony, Nowak, Radosław P., Attwood, Martin, Cockman, Matthew E., Oppermann, Udo, Loenarz, Christoph, Schofield, Christopher J.
Publicado no Chemistry (2019)

Factor-inhibiting hypoxia-inducible factor (FIH) catalyses the post-translational hydroxylation of histidinyl residues within ankyrin repeat domains

Por Yang, Ming, Chowdhury, Rasheduzzaman, Ge, Wei, Hamed, Refaat B, McDonough, Michael A, Claridge, Timothy D W, Kessler, Benedikt M, Cockman, Matthew E, Ratcliffe, Peter J, Schofield, Christopher J
Publicado em 2011

Hydroxylation of the eukaryotic ribosomal decoding center affects translational accuracy

Por Loenarz, Christoph, Sekirnik, Rok, Thalhammer, Armin, Ge, Wei, Spivakovsky, Ekaterina, Mackeen, Mukram M., McDonough, Michael A., Cockman, Matthew E., Kessler, Benedikt M., Ratcliffe, Peter J., Wolf, Alexander, Schofield, Christopher J.
Publicado em 2014

Posttranslational hydroxylation of ankyrin repeats in IκB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)

Por Cockman, Matthew E., Lancaster, David E., Stolze, Ineke P., Hewitson, Kirsty S., McDonough, Michael A., Coleman, Mathew L., Coles, Charlotte H., Yu, Xiaohong, Hay, Ronald T., Ley, Steven C., Pugh, Christopher W., Oldham, Neil J., Masson, Norma, Schofield, Christopher J., Ratcliffe, Peter J.
Publicado em 2006

Sudestada1, a Drosophila ribosomal prolyl-hydroxylase required for mRNA translation, cell homeostasis, and organ growth

Por Katz, Maximiliano J., Acevedo, Julieta M., Loenarz, Christoph, Galagovsky, Diego, Liu-Yi, Phebee, Pérez-Pepe, Marcelo, Thalhammer, Armin, Sekirnik, Rok, Ge, Wei, Melani, Mariana, Thomas, María G., Simonetta, Sergio, Boccaccio, Graciela L., Schofield, Christopher J., Cockman, Matthew E., Ratcliffe, Peter J., Wappner, Pablo
Publicado em 2014

OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation

Por Singleton, Rachelle S., Liu-Yi, Phebee, Formenti, Fabio, Ge, Wei, Sekirnik, Rok, Fischer, Roman, Adam, Julie, Pollard, Patrick J., Wolf, Alexander, Thalhammer, Armin, Loenarz, Christoph, Flashman, Emily, Yamamoto, Atsushi, Coleman, Mathew L., Kessler, Benedikt M., Wappner, Pablo, Schofield, Christopher J., Ratcliffe, Peter J., Cockman, Matthew E.
Publicado em 2014

Optimal Translational Termination Requires C4 Lysyl Hydroxylation of eRF1

Por Feng, Tianshu, Yamamoto, Atsushi, Wilkins, Sarah E., Sokolova, Elizaveta, Yates, Luke A., Münzel, Martin, Singh, Pooja, Hopkinson, Richard J., Fischer, Roman, Cockman, Matthew E., Shelley, Jake, Trudgian, David C., Schödel, Johannes, McCullagh, James S.O., Ge, Wei, Kessler, Benedikt M., Gilbert, Robert J., Frolova, Ludmila Y., Alkalaeva, Elena, Ratcliffe, Peter J., Schofield, Christopher J., Coleman, Mathew L.
Publicado em 2014

A Ribosomopathy Reveals Decoding Defective Ribosomes Driving Human Dysmorphism

Por Paolini, Nahuel A., Attwood, Martin, Sondalle, Samuel B., Vieira, Carolina Marques dos Santos, van Adrichem, Anita M., di Summa, Franca M., O’Donohue, Marie-Françoise, Gleizes, Pierre-Emmanuel, Rachuri, Swaksha, Briggs, Joseph W., Fischer, Roman, Ratcliffe, Peter J., Wlodarski, Marcin W., Houtkooper, Riekelt H., von Lindern, Marieke, Kuijpers, Taco W., Dinman, Jonathan D., Baserga, Susan J., Cockman, Matthew E., MacInnes, Alyson W.
Publicado no Am J Hum Genet (2017)

The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases

Por Markolovic, Suzana, Zhuang, Qinqin, Wilkins, Sarah E, Eaton, Charlotte D, Abboud, Martine I, Katz, Maximiliano J, McNeil, Helen E, Leśniak, Robert K, Hall, Charlotte, Struwe, Weston B, Konietzny, Rebecca, Davis, Simon, Yang, Ming, Ge, Wei, Benesch, Justin LP, Kessler, Benedikt M, Ratcliffe, Peter J, Cockman, Matthew E, Fischer, Roman, Wappner, Pablo, Chowdhury, Rasheduzzaman, Coleman, Mathew L, Schofield, Christopher J
Publicado no Nat Chem Biol (2018)

Oxygenase Catalysed Ribosome Hydroxylation Occurs in Prokaryotes and Humans

Por Ge, Wei, Wolf, Alexander, Feng, Tianshu, Ho, Chia-hua, Sekirnik, Rok, Zayer, Adam, Granatino, Nicolas, Cockman, Matthew E., Loenarz, Christoph, Loik, Nikita D., Hardy, Adam P., Claridge, Timothy D.W., Hamed, Refaat B., Chowdhury, Rasheduzzaman, Gong, Lingzhi, Robinson, Carol V., Trudgian, David C., Jiang, Miao, Mackeen, Mukram M., Mccullagh, James S., Gordiyenko, Yuliya, Thalhammer, Armin, Yamamoto, Atsushi, Yang, Ming, Liu-Yi, Phebee, Zhang, Zhihong, Schmidt-Zachmann, Marion, Kessler, Benedikt M., Ratcliffe, Peter J., Preston, Gail M., Coleman, Mathew L., Schofield, Christopher J.
Publicado no Nat Chem Biol (2012)