The DNAJA2 Substrate Release Mechanism Is Essential for Chaperone-mediated Folding

DNAJA1 (DJA1/Hdj2) and DNAJA2 (DJA2) are the major J domain partners of human Hsp70/Hsc70 chaperones. Although they have overall similarity with the well characterized type I co-chaperones from yeast and bacteria, they are biologically distinct, and their functional mechanisms are poorly characteriz...

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Dades bibliogràfiques
Autors principals: Baaklini, Imad, Wong, Michael J. H., Hantouche, Christine, Patel, Yogita, Shrier, Alvin, Young, Jason C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
Matèries:
Protein Structure and Folding
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516741/
https://ncbi.nlm.nih.gov/pubmed/23091061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.413278
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