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Functional Divergence between Co-chaperones of Hsc70()

The ATPase cycle of the chaperone Hsc70 is regulated by co-chaperones; Hsp40/DnaJ-related proteins stimulate ATP hydrolysis by Hsc70 and can bind unfolded polypeptides themselves. Conversely, various nucleotide exchange factors (NEFs) stimulate ADP-ATP exchange by Hsc70. We analyzed the purified Hsp...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Tzankov, Stefan, Wong, Michael J. H., Shi, Kun, Nassif, Christina, Young, Jason C.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026489/
https://ncbi.nlm.nih.gov/pubmed/18684711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803923200
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