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Non-canonical Interactions between Heat Shock Cognate Protein 70 (Hsc70) and Bcl2-associated Anthanogene (BAG) Co-Chaperones Are Important for Client Release

Heat shock cognate protein 70 (Hsc70) regulates protein homeostasis through its reversible interactions with client proteins. Hsc70 has two major domains: a nucleotide-binding domain (NBD), that hydrolyzes ATP, and a substrate-binding domain (SBD), where clients are bound. Members of the BAG family...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Biol Chem
Päätekijät: Rauch, Jennifer N., Zuiderweg, Erik R. P., Gestwicki, Jason E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025674/
https://ncbi.nlm.nih.gov/pubmed/27474739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.742502
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