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The disorderly conduct of Hsc70 and its interaction with the Alzheimer's-related Tau protein
Hsp70 chaperones bind to various protein substrates for folding, trafficking, and degradation. Considerable structural information is available about how prokaryotic Hsp70 (DnaK) binds substrates, but less is known about mammalian Hsp70s, of which there are 13 isoforms encoded in the human genome. H...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6036187/ https://ncbi.nlm.nih.gov/pubmed/29764935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002234 |
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