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Crystallization of a functionally intact Hsc70 chaperone

Hsp70s are essential chaperones with roles in a variety of cellular processes and representatives in all kingdoms of life. They are comprised of a nucleotide-binding domain (NBD) and a protein substrate-binding domain (SBD). Structures of isolated NBDs and SBDs have been reported but, until recently...

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Autori principali: Jiang, Jianwen, Lafer, Eileen M., Sousa, Rui
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Union of Crystallography 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2150933/
https://ncbi.nlm.nih.gov/pubmed/16511258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309105040303
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