Functional Interaction of Aurora-A and PP2A during Mitosis

por Horn, Virginie, Thélu, Jacques, Garcia, Alphonse, Albigès-Rizo, Corinne, Block, Marc R., Viallet, Jean
Publicado 2007

Anti-Metastatic and Anti-Tumor Growth Effects of Origanum majorana on Highly Metastatic Human Breast Cancer Cells: Inhibition of NFκB Signaling and Reduction of Nitric Oxide Produ...

por Al Dhaheri, Yusra, Attoub, Samir, Arafat, Kholoud, AbuQamar, Synan, Viallet, Jean, Saleh, Alaaeldin, Al Agha, Hala, Eid, Ali, Iratni, Rabah
Publicado 2013

Phase I study of obatoclax mesylate (GX15-070), a small molecule pan–Bcl-2 family antagonist, in patients with advanced chronic lymphocytic leukemia

por O'Brien, Susan M., Claxton, David F., Crump, Michael, Faderl, Stefan, Kipps, Thomas, Keating, Michael J., Viallet, Jean, Cheson, Bruce D.
Publicado en Blood (2009)

Mechanisms of antileukemic activity of the novel BH3 mimetic GX15-070 (obatoclax)

por Konopleva, Marina, Watt, Julie, Contractor, Rooha, Tsao, Twee, Harris, David, Estrov, Zeev, Bornmann, William, Kantarjian, Hagop, Viallet, Jean, Samudio, Ismael, Andreeff, Michael
Publicado 2008

THE COMBINATION OF A HISTONE DEACETYLASE INHIBITOR WITH THE BH3-MIMETIC GX15-070 HAS SYNERGISTIC ANTILEUKEMIA ACTIVITY BY ACTIVATING BOTH APOPTOTSIS AND AUTOPHAGY

por Wei, Yue, Kadia, Tapan, Tong, Weigang, Zhang, Ming, Jia, Yu, Yang, Hui, Hu, Yumin, Viallet, Jean, O’Brien, Susan, Garcia-Manero, Guillermo
Publicado 2010

Phase I Dose Finding Studies of Obatoclax (GX15-070), a Small Molecule Pan-BCL-2 Family Antagonist, in Patients with Advanced Solid Tumors or Lymphoma

por Hwang, Jimmy J., Kuruvilla, John, Mendelson, David, Pishvaian, Michael J., Deeken, J.F., Siu, Lillian L., Berger, Mark S., Viallet, Jean, Marshall, John L.
Publicado 2010

Rhus coriaria suppresses angiogenesis, metastasis and tumor growth of breast cancer through inhibition of STAT3, NFκB and nitric oxide pathways

por El Hasasna, Hussain, Saleh, Alaaeldin, Samri, Halima Al, Athamneh, Khawlah, Attoub, Samir, Arafat, Kholoud, Benhalilou, Nehla, Alyan, Sofyan, Viallet, Jean, Dhaheri, Yusra Al, Eid, Ali, Iratni, Rabah
Publicado en Sci Rep (2016)

Metabolic Signatures of Tumor Responses to Doxorubicin Elucidated by Metabolic Profiling in Ovo

por Achkar, Iman W., Kader, Sara, Dib, Shaima S., Junejo, Kulsoom, Al-Bader, Salha Bujassoum, Hayat, Shahina, Bhagwat, Aditya M., Rousset, Xavier, Wang, Yan, Viallet, Jean, Suhre, Karsten, Halama, Anna
Publicado en Metabolites (2020)

Small molecule obatoclax (GX15-070) antagonizes MCL-1 and overcomes MCL-1-mediated resistance to apoptosis

por Nguyen, Mai, Marcellus, Richard C., Roulston, Anne, Watson, Mark, Serfass, Lucile, Murthy Madiraju, S. R., Goulet, Daniel, Viallet, Jean, Bélec, Laurent, Billot, Xavier, Acoca, Stephane, Purisima, Enrico, Wiegmans, Adrian, Cluse, Leonie, Johnstone, Ricky W., Beauparlant, Pierre, Shore, Gordon C.
Publicado 2007

Azaindole derivatives are inhibitors of microtubule dynamics, with anti-cancer and anti-angiogenic activities

por Prudent, Renaud, Vassal-Stermann, Émilie, Nguyen, Chi-Hung, Mollaret, Marjorie, Viallet, Jean, Desroches-Castan, Agnès, Martinez, Anne, Barette, Caroline, Pillet, Catherine, Valdameri, Glaucio, Soleilhac, Emmanuelle, Di Pietro, Attilio, Feige, Jean-Jacques, Billaud, Marc, Florent, Jean-Claude, Lafanechère, Laurence
Publicado 2013