Chemogenomics and chemical genetics a user's introduction for biologists, chemists and informaticians /

di Marechal, ERIC., Roy, Sylvaine., Lafanechère, Laurence.
Pubblicazione c201

Targeting LIM kinases in taxane resistant tumors

di Prunier, Chloé, Kapur, Reuben, Lafanechère, Laurence
Pubblicato in Oncotarget (2016)

LIM kinases: cofilin and beyond

di Prunier, Chloé, Prudent, Renaud, Kapur, Reuben, Sadoul, Karin, Lafanechère, Laurence
Pubblicato in Oncotarget (2017)

Molecular crosstalk between apoptosis and autophagy induced by a novel 2-methoxyestradiol analogue in cervical adenocarcinoma cells

di Theron, Anne E, Nolte, Elsie M, Lafanechère, Laurence, Joubert, Annie M
Pubblicazione 2013

STOP Proteins are Responsible for the High Degree of Microtubule Stabilization Observed in Neuronal Cells

di Guillaud, Laurent, Bosc, Christophe, Fourest-Lieuvin, Anne, Denarier, Eric, Pirollet, Fabienne, Lafanechère, Laurence, Job, Didier
Pubblicazione 1998

Sulphamoylated 2-Methoxyestradiol Analogues Induce Apoptosis in Adenocarcinoma Cell Lines

di Visagie, Michelle, Theron, Anne, Mqoco, Thandi, Vieira, Warren, Prudent, Renaud, Martinez, Anne, Lafanechère, Laurence, Joubert, Annie
Pubblicazione 2013

LIMK Regulates Tumor-Cell Invasion and Matrix Degradation Through Tyrosine Phosphorylation of MT1-MMP

di Lagoutte, Emilie, Villeneuve, Clémentine, Lafanechère, Laurence, Wells, Claire M., Jones, Gareth E., Chavrier, Philippe, Rossé, Carine
Pubblicato in Sci Rep (2016)

A proteomic-informed view of the changes induced by loss of cellular adherence: The example of mouse macrophages

di Ramirez Rios, Sacnite, Torres, Anaelle, Diemer, Hélène, Collin-Faure, Véronique, Cianférani, Sarah, Lafanechère, Laurence, Rabilloud, Thierry
Pubblicato in PLoS One (2021)

Motor-dependent microtubule disassembly driven by tubulin tyrosination

di Peris, Leticia, Wagenbach, Michael, Lafanechère, Laurence, Brocard, Jacques, Moore, Ayana T., Kozielski, Frank, Job, Didier, Wordeman, Linda, Andrieux, Annie
Pubblicazione 2009

Antitumoral activity of allosteric inhibitors of protein kinase CK2

di Moucadel, Virginie, Prudent, Renaud, Sautel, Céline F., Teillet, Florence, Barette, Caroline, Lafanechere, Laurence, Receveur-Brechot, Veronique, Cochet, Claude
Pubblicazione 2011

A quantitative proteomic analysis of cofilin phosphorylation in myeloid cells and its modulation using the LIM kinase inhibitor Pyr1

di Prudent, Renaud, Demoncheaux, Nathalie, Diemer, Hélène, Collin-Faure, Véronique, Kapur, Reuben, Paublant, Fabrice, Lafanechère, Laurence, Cianférani, Sarah, Rabilloud, Thierry
Pubblicato in PLoS One (2018)

Benzo[e]pyridoindoles, novel inhibitors of the aurora kinases

di Hoang, Thi My-Nhung, Favier, Bertrand, Valette, Annie, Barette, Caroline, Nguyen, Chi Hung, Lafanechère, Laurence, Grierson, David S., Dimitrov, Stéfan, Molla, Annie
Pubblicazione 2009

Characterization of Signalling Pathways That Link Apoptosis and Autophagy to Cell Death Induced by Estrone Analogues Which Reversibly Depolymerize Microtubules

di Mercier, Anne E., Prudent, Renaud, Pepper, Michael S., De Koning, Leanne, Nolte, Elsie, Peronne, Lauralie, Nel, Marcel, Lafanechère, Laurence, Joubert, Anna M.
Pubblicato in Molecules (2021)

β3 integrin–mediated spreading induced by matrix-bound BMP-2 controls Smad signaling in a stiffness-independent manner

di Fourel, Laure, Valat, Anne, Faurobert, Eva, Guillot, Raphael, Bourrin-Reynard, Ingrid, Ren, Kefeng, Lafanechère, Laurence, Planus, Emmanuelle, Picart, Catherine, Albiges-Rizo, Corinne
Pubblicato in J Cell Biol (2016)

A New Quantitative Cell-Based Assay Reveals Unexpected Microtubule Stabilizing Activity of Certain Kinase Inhibitors, Clinically Approved or in the Process of Approval

di Ramirez-Rios, Sacnicte, Michallet, Sophie, Peris, Leticia, Barette, Caroline, Rabat, Clotilde, Feng, Yangbo, Fauvarque, Marie-Odile, Andrieux, Annie, Sadoul, Karin, Lafanechère, Laurence
Pubblicato in Front Pharmacol (2020)

Pyr1-Mediated Pharmacological Inhibition of LIM Kinase Restores Synaptic Plasticity and Normal Behavior in a Mouse Model of Schizophrenia

di Gory-Fauré, Sylvie, Powell, Rebecca, Jonckheere, Julie, Lanté, Fabien, Denarier, Eric, Peris, Leticia, Nguyen, Chi Hung, Buisson, Alain, Lafanechère, Laurence, Andrieux, Annie
Pubblicato in Front Pharmacol (2021)

A new chemical inhibitor of angiogenesis and tumorigenesis that targets the VEGF signaling pathway upstream of Ras

di Desroches-Castan, Agnès, Quélard, Delphine, Demeunynck, Martine, Constant, Jean-François, Dong, Chongling, Keramidas, Michelle, Coll, Jean-Luc, Barette, Caroline, Lafanechère, Laurence, Feige, Jean-Jacques
Pubblicato in Oncotarget (2015)

Acacetin and Chrysin, Two Polyphenolic Compounds, Alleviate Telomeric Position Effect in Human Cells

di Boussouar, Amina, Barette, Caroline, Nadon, Robert, Saint-Léger, Adelaïde, Broucqsault, Natacha, Ottaviani, Alexandre, Firozhoussen, Arva, Lu, Yiming, Lafanechère, Laurence, Gilson, Eric, Magdinier, Frédérique, Ye, Jing
Pubblicazione 2013

Tubulin tyrosination is a major factor affecting the recruitment of CAP-Gly proteins at microtubule plus ends

di Peris, Leticia, Thery, Manuel, Fauré, Julien, Saoudi, Yasmina, Lafanechère, Laurence, Chilton, John K., Gordon-Weeks, Phillip, Galjart, Niels, Bornens, Michel, Wordeman, Linda, Wehland, Juergen, Andrieux, Annie, Job, Didier
Pubblicazione 2006

Identification of pyrrolopyrimidine derivative PP-13 as a novel microtubule-destabilizing agent with promising anticancer properties

di Gilson, Pauline, Josa-Prado, Fernando, Beauvineau, Claire, Naud-Martin, Delphine, Vanwonterghem, Laetitia, Mahuteau-Betzer, Florence, Moreno, Alexis, Falson, Pierre, Lafanechère, Laurence, Frachet, Véronique, Coll, Jean-Luc, Fernando Díaz, Jose, Hurbin, Amandine, Busser, Benoit
Pubblicato in Sci Rep (2017)