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Motor-dependent microtubule disassembly driven by tubulin tyrosination
In cells, stable microtubules (MTs) are covalently modified by a carboxypeptidase, which removes the C-terminal Tyr residue of α-tubulin. The significance of this selective detyrosination of MTs is not understood. In this study, we report that tubulin detyrosination in fibroblasts inhibits MT disass...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Rockefeller University Press
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2712961/ https://ncbi.nlm.nih.gov/pubmed/19564401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200902142 |
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