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Microtubule Regulation in Mitosis: Tubulin Phosphorylation by the Cyclin-dependent Kinase Cdk1

The activation of the cyclin-depdndent kinase Cdk1 at the transition from interphase to mitosis induces important changes in microtubule dynamics. Cdk1 phosphorylates a number of microtubule- or tubulin-binding proteins but, hitherto, tubulin itself has not been detected as a Cdk1 substrate. Here we...

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Bibliografiske detaljer
Main Authors: Fourest-Lieuvin, Anne, Peris, Leticia, Gache, Vincent, Garcia-Saez, Isabel, Juillan-Binard, Céline, Lantez, Violaine, Job, Didier
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1382296/
https://ncbi.nlm.nih.gov/pubmed/16371510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-07-0621
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