Benzo[e]pyridoindoles, novel inhibitors of the aurora kinases

Aurora kinases are serine/threonine protein kinases that are involved in cancer development and are important targets for cancer therapy. By high throughput screening of a chemical library we found that benzo[e]pyridoindole derivatives inhibited Aurora kinase. The most potent compound (compound 1) w...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Hoang, Thi My-Nhung, Favier, Bertrand, Valette, Annie, Barette, Caroline, Nguyen, Chi Hung, Lafanechère, Laurence, Grierson, David S., Dimitrov, Stéfan, Molla, Annie
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2009
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325905/
https://ncbi.nlm.nih.gov/pubmed/19221479
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki