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Basal aurora kinase B activity is sufficient for histone H3 phosphorylation in prophase
Histone H3 phosphorylation is the hallmark of mitosis deposited by aurora kinase B. Benzo[e]pyridoindoles are a family of potent, broad, ATP-competitive aurora kinase inhibitors. However, benzo[e]pyridoindole C4 only inhibits histone H3 phosphorylation in prophase but not in metaphase. Under the C4...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Company of Biologists
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3625866/ https://ncbi.nlm.nih.gov/pubmed/23616922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20133079 |
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