Pyr1-Mediated Pharmacological Inhibition of LIM Kinase Restores Synaptic Plasticity and Normal Behavior in a Mouse Model of Schizophrenia

The search for effective treatments for neuropsychiatric disorders is ongoing, with progress being made as brain structure and neuronal function become clearer. The central roles played by microtubules (MT) and actin in synaptic transmission and plasticity suggest that the cytoskeleton and its modul...

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Foilsithe in:Front Pharmacol
Main Authors: Gory-Fauré, Sylvie, Powell, Rebecca, Jonckheere, Julie, Lanté, Fabien, Denarier, Eric, Peris, Leticia, Nguyen, Chi Hung, Buisson, Alain, Lafanechère, Laurence, Andrieux, Annie
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2021
Ábhair:
Pharmacology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8006432/
https://ncbi.nlm.nih.gov/pubmed/33790791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.627995
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