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A quantitative proteomic analysis of cofilin phosphorylation in myeloid cells and its modulation using the LIM kinase inhibitor Pyr1

LIM kinases are located at a strategic crossroad, downstream of several signaling pathways and upstream of effectors such as microtubules and the actin cytoskeleton. Cofilin is the only LIM kinases substrate that is well described to date, and its phosphorylation on serine 3 by LIM kinases controls...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Prudent, Renaud, Demoncheaux, Nathalie, Diemer, Hélène, Collin-Faure, Véronique, Kapur, Reuben, Paublant, Fabrice, Lafanechère, Laurence, Cianférani, Sarah, Rabilloud, Thierry
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294390/
https://ncbi.nlm.nih.gov/pubmed/30550596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0208979
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