Integration of pan-cancer transcriptomics with RPPA proteomics reveals mechanisms of epithelial-mesenchymal transition

द्वारा Koplev, Simon, Lin, Katie, Dohlman, Anders B., Ma’ayan, Avi
में प्रकाशित PLoS Comput Biol (2018)

Macrophage Trafficking, Inflammatory Resolution, and Genomics in Atherosclerosis: JACC Macrophage in CVD Series (Part II)

द्वारा Moore, Kathryn J., Koplev, Simon, Fisher, Edward A., Tabas, Ira, Björkegren, Johan L.M., Doran, Amanda C., Kovacic, Jason C
में प्रकाशित J Am Coll Cardiol (2018)

Systems Pharmacology Identifies an Arterial Wall Regulatory Gene Network Mediating Coronary Artery Disease Side Effects of Antiretroviral Therapy

द्वारा Frades, Itziar, Readhead, Ben, Amadori, Letizia, Koplev, Simon, Talukdar, Husain A., Crane, Heidi M., Crane, Paul K., Kovacic, Jason C., Dudley, Joel T., Giannarelli, Chiara, Björkegren, Johan LM., Peter, Inga
में प्रकाशित Circ Genom Precis Med (2019)

Contribution of Regulatory-Gene Networks to Heritability of Coronary Artery Disease

द्वारा Zeng, Lingyao, Talukdar, Husain, Koplev, Simon, Giannarelli, Chiara, Ivert, Torbjörn, Gan, Li-Ming, Ruusalepp, Arno, Schadt, Eric E, Kovacic, Jason C., Lusis, Aldons J., Michoel, Tom, Schunkert, Heribert, Björkegren, Johan L.M.
में प्रकाशित J Am Coll Cardiol (2019)

Sex-stratified gene regulatory networks reveal female key-driver genes of atherosclerosis involved in smooth muscle cell phenotype switching

द्वारा Hartman, Robin J.G., Owsiany, Katie, Ma, Lijiang, Koplev, Simon, Hao, Ke, Slenders, Lotte, Civelek, Mete, Mokry, Michal, Kovacic, Jason C., Pasterkamp, Gerard, Owens, Gary, Björkegren, Johan L.M., den Ruijter, Hester M.
में प्रकाशित Circulation (2021)

Developing a Framework for Digital Objects in the Big Data to Knowledge (BD2K) Commons: Report from the Commons Framework Pilots Workshop

द्वारा Jagodnik, Kathleen M., Koplev, Simon, Jenkins, Sherry, Ohno-Machado, Lucila, Paten, Benedict, Schurer, Stephan C., Dumontier, Michel, Verborgh, Ruben, Bui, Alex, Ping, Peipei, McKenna, Neil J., Madduri, Ravi, Pillai, Ajay, Ma’ayan, Avi
में प्रकाशित J Biomed Inform (2017)

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

द्वारा Kuleshov, Maxim V., Jones, Matthew R., Rouillard, Andrew D., Fernandez, Nicolas F., Duan, Qiaonan, Wang, Zichen, Koplev, Simon, Jenkins, Sherry L., Jagodnik, Kathleen M., Lachmann, Alexander, McDermott, Michael G., Monteiro, Caroline D., Gundersen, Gregory W., Ma'ayan, Avi
में प्रकाशित Nucleic Acids Res (2016)

The JCAD gene at the 10p11 coronary artery disease locus regulates Hippo signaling in endothelial cells

द्वारा Jones, Peter D., Kaiser, Michael A., Ghaderi Najafabadi, Maryam, Koplev, Simon, Zhao, Yuqi, Douglas, Gillian, Kyriakou, Theodosios, Andrews, Sarah, Rajmohan, Rathinasabapathy, Watkins, Hugh, Channon, Keith M., Ye, Shu, Yang, Xia, Björkegren, Johan L. M., Samani, Nilesh J., Webb, Tom R.
में प्रकाशित Arterioscler Thromb Vasc Biol (2018)

Functional regulatory mechanism of smooth muscle cell-restricted LMOD1 coronary artery disease locus

द्वारा Nanda, Vivek, Wang, Ting, Pjanic, Milos, Liu, Boxiang, Nguyen, Trieu, Matic, Ljubica Perisic, Hedin, Ulf, Koplev, Simon, Ma, Lijiang, Franzén, Oscar, Ruusalepp, Arno, Schadt, Eric E., Björkegren, Johan L. M., Montgomery, Stephen B., Snyder, Michael P., Quertermous, Thomas, Leeper, Nicholas J., Miller, Clint L.
में प्रकाशित PLoS Genet (2018)

Functional and Transcriptomic Insights into Pathogenesis of R9C Phospholamban Mutation using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes

द्वारा Ceholski, Delaine K., Turnbull, Irene C., Kong, Chi-Wing, Koplev, Simon, Mayourian, Joshua, Gorski, Przemek A., Stillitano, Francesca, Skodras, Angelos A., Nonnenmacher, Mathieu, Cohen, Ninette, Björkegren, Johan LM, Stroik, Daniel R., Cornea, Razvan L., Thomas, David D., Li, Ronald A., Costa, Kevin D., Hajjar, Roger J.
में प्रकाशित J Mol Cell Cardiol (2018)

CD90 Identifies Adventitial Mesenchymal Progenitor Cells in Adult Human Medium- and Large-Sized Arteries

द्वारा Michelis, Katherine C., Nomura-Kitabayashi, Aya, Lecce, Laura, Franzén, Oscar, Koplev, Simon, Xu, Yang, Santini, Maria Paola, D'Escamard, Valentina, Lee, Jonathan T.L., Fuster, Valentin, Hajjar, Roger, Reddy, Ramachandra C., Chikwe, Joanna, Stelzer, Paul, Filsoufi, Farzan, Stewart, Allan, Anyanwu, Anelechi, Björkegren, Johan L.M., Kovacic, Jason C.
में प्रकाशित Stem Cell Reports (2018)

Histone deacetylase 9 promotes endothelial-mesenchymal transition and an unfavorable atherosclerotic plaque phenotype

द्वारा Lecce, Laura, Xu, Yang, V’Gangula, Bhargavi, Chandel, Nirupama, Pothula, Venu, Caudrillier, Axelle, Santini, Maria Paola, d’Escamard, Valentina, Ceholski, Delaine K., Gorski, Przemek A., Ma, Lijiang, Koplev, Simon, Bjørklund, Martin Mæng, Björkegren, Johan L.M., Boehm, Manfred, Bentzon, Jacob Fog, Fuster, Valentin, Kim, Ha Won, Weintraub, Neal L., Baker, Andrew H., Bernstein, Emily, Kovacic, Jason C.
में प्रकाशित J Clin Invest (2021)

Clonally expanding smooth muscle cells promote atherosclerosis by escaping efferocytosis and activating the complement cascade

द्वारा Wang, Ying, Nanda, Vivek, Direnzo, Daniel, Ye, Jianqin, Xiao, Sophia, Kojima, Yoko, Howe, Kathryn L., Jarr, Kai-Uwe, Flores, Alyssa M., Tsantilas, Pavlos, Tsao, Noah, Rao, Abhiram, Newman, Alexandra A. C., Eberhard, Anne V., Priest, James R., Ruusalepp, Arno, Pasterkamp, Gerard, Maegdefessel, Lars, Miller, Clint L., Lind, Lars, Koplev, Simon, Björkegren, Johan L. M., Owens, Gary K., Ingelsson, Erik, Weissman, Irving L., Leeper, Nicholas J.
में प्रकाशित Proc Natl Acad Sci U S A (2020)

An integrative multiomic network model links lipid metabolism to glucose regulation in coronary artery disease

द्वारा Cohain, Ariella T., Barrington, William T., Jordan, Daniel M., Beckmann, Noam D., Argmann, Carmen A., Houten, Sander M., Charney, Alexander W., Ermel, Raili, Sukhavasi, Katyayani, Franzen, Oscar, Koplev, Simon, Whatling, Carl, Belbin, Gillian M., Yang, Jialiang, Hao, Ke, Kenny, Eimear E., Tu, Zhidong, Zhu, Jun, Gan, Li-Ming, Do, Ron, Giannarelli, Chiara, Kovacic, Jason C., Ruusalepp, Arno, Lusis, Aldons J., Bjorkegren, Johan L. M., Schadt, Eric E.
में प्रकाशित Nat Commun (2021)

A strategy for discovery of endocrine interactions with application to whole-body metabolism

द्वारा Seldin, Marcus M., Koplev, Simon, Rajbhandari, Prashant, Vergnes, Laurent, Rosenberg, Gregory M., Meng, Yonghong, Pan, Calvin, Phuong, Thuy M.N., Gharakhanian, Raffi, Che, Nam, Mäkinen, Selina, Shih, Diana M., Civelek, Mete, Parks, Brian W., Kim, Eric D., Norheim, Frode, Krishnan, Karthickeyan Chella, Hasin-Brumshtein, Yehudit, Mehrabian, Margarete, Laakso, Markku, Drevon, Christian A., Koistinen, Heikki A., Tontonoz, Peter, Reue, Karen, Cantor, Rita M., Björkegren, Johan L. M., Lusis, Aldons J.
में प्रकाशित Cell Metab (2018)

The Library of Integrated Network-based Cellular Signatures (LINCS) NIH Program: System-level Cataloging of Human Cells Response to Perturbations

द्वारा Keenan, Alexandra B., Jenkins, Sherry L., Jagodnik, Kathleen M., Koplev, Simon, He, Edward, Torre, Denis, Wang, Zichen, Dohlman, Anders B., Silverstein, Moshe C., Lachmann, Alexander, Kuleshov, Maxim V., Ma’ayan, Avi, Stathias, Vasileios, Terryn, Raymond, Cooper, Daniel, Forlin, Michele, Koleti, Amar, Vidovic, Dusica, Chung, Caty, Schürer, Stephan C., Vasiliauskas, Jouzas, Pilarczyk, Marcin, Shamsaei, Behrouz, Fazel, Mehdi, Ren, Yan, Niu, Wen, Clark, Nicholas A., White, Shana, Mahi, Naim, Zhang, Lixia, Kouril, Michal, Reichard, John F., Sivaganesan, Siva, Medvedovic, Mario, Meller, Jaroslaw, Koch, Rick J., Birtwistle, Marc R., Iyengar, Ravi, Sobie, Eric A., Azeloglu, Evren, Kaye, Julia, Osterloh, Jeannette, Haston, Kelly, Kalra, Jaslin, Finkbiener, Steve M., Li, Jonathan, Milani, Pamela, Adam, Miriam, Escalante, Renan, Sachs, Karen, Lenail, Alex, Ramamoorthy, Divya, Fraenkel, Ernest, Daigle, Gavin, Hussain, Uzma, Coye, Alyssa, Rothstein, Jeffrey, Sareen, Dhruv, Ornelas, Loren, Banuelos, Maria, Mandefro, Berhan, Ho, Ritchie, Svendsen, Clive N., Lim, Ryan, Stocksdale, Jennifer, Casale, Malcolm, Thompson, Terri, Wu, Jenny, Thompson, Leslie M., Dardov, Victoria, Venkatraman, Vidya, Matlock, Andrea, Van Eyk, Jenny, Jaffe, Jacob D., Papanastasiou, Malvina, Subramanian, Aravind, Golub, Todd R., Erickson, Sean D., Fallahi-Sichani, Mohammad, Hafner, Marc, Gray, Nathanael S., Lin, Jia-Ren, Mills, Caitlin E., Muhlich, Jeremy L., Niepel, Mario, Shamu, Caroline E., Williams, Elizabeth H., Wrobel, David, Sorger, Peter K., Heiser, Laura M., Gray, Joe W., Korkola, James E., Mills, Gordon B., LaBarge, Mark, Feiler, Heidi S., Dane, Mark A., Bucher, Elmar, Nederlof, Michel, Sudar, Damir, Gross, Sean, Kilburn, David F., Smith, Rebecca, Devlin, Kaylyn, Margolis, Ron, Derr, Leslie, Lee, Albert, Pilai, Ajay
में प्रकाशित Cell Syst (2017)

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

द्वारा Malik, Rainer, Chauhan, Ganesh, Traylor, Matthew, Sargurupremraj, Muralidharan, Okada, Yukinori, Mishra, Aniket, Rutten-Jacobs, Loes, Giese, Anne-Katrin, van der Laan, Sander W., Gretarsdottir, Solveig, Anderson, Christopher D., Chong, Michael, Adams, Hieab H. H., Ago, Tetsuro, Almgren, Peter, Amouyel, Philippe, Ay, Hakan, Bartz, Traci M., Benavente, Oscar R., Bevan, Steve, Boncoraglio, Giorgio B., Brown, Robert D., Butterworth, Adam S., Carrera, Caty, Carty, Cara L., Chasman, Daniel I., Chen, Wei-Min, Cole, John W., Correa, Adolfo, Cotlarciuc, Ioana, Cruchaga, Carlos, Danesh, John, de Bakker, Paul I. W., DeStefano, Anita L., den Hoed, Marcel, Duan, Qing, Engelter, Stefan T., Falcone, Guido J., Gottesman, Rebecca F., Grewal, Raji P., Gudnason, Vilmundur, Gustafsson, Stefan, Haessler, Jeffrey, Harris, Tamara B., Hassan, Ahamad, Havulinna, Aki S., Heckbert, Susan R., Holliday, Elizabeth G., Howard, George, Hsu, Fang-Chi, Hyacinth, Hyacinth I., Ikram, M. Arfan, ingelsson, Erik, Irvin, Marguerite R., Jian, Xueqiu, Jimenez-Conde, Jordi, Johnson, Julie A., Jukema, J. Wouter, Kanai, Masahiro, Keene, Keith L., Kissela, Brett M., Kleindorfer, Dawn O., Kooperberg, Charles, Kubo, Michiaki, Lange, Leslie A., Langefeld, Carl D., Langenberg, Claudia, Launer, Lenore J., Lee, Jin-Moo, Lemmens, Robin, Leys, Didier, Lewis, Cathryn M., Lin, Wei-Yu, Lindgren, Arne G., Lorentzen, Erik, Magnusson, Patrik K., Maguire, Jane, Manichaikul, Ani, McArdle, Patrick F., Meschia, James F., Mitchell, Braxton D., Mosley, Thomas H., Nalls, Michael A., Ninomiya, Toshiharu, O’Donnell, Martin J., Psaty, Bruce M., Pulit, Sara L., Rannikmäe, Kristiina, Reiner, Alexander P., Rexrode, Kathryn M., Rice, Kenneth, Rich, Stephen S., Ridker, Paul M., Rost, Natalia S., Rothwell, Peter M., Rotter, Jerome I., Rundek, Tatjana, Sacco, Ralph L., Sakaue, Saori, Sale, Michele M., Salomaa, Veikko, Sapkota, Bishwa R., Schmidt, Reinhold, Schmidt, Carsten O., Schminke, Ulf, Sharma, Pankaj, Slowik, Agnieszka, Sudlow, Cathie L. M., Tanislav, Christian, Tatlisumak, Turgut, Taylor, Kent D., Thijs, Vincent N. S., Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Tiedt, Steffen, Trompet, Stella, Tzourio, Christophe, van Duijn, Cornelia M., Walters, Matthew, Wareham, Nicholas J., Wassertheil-Smoller, Sylvia, Wilson, James G., Wiggins, Kerri L., Yang, Qiong, Yusuf, Salim, Bis, Joshua C., Pastinen, Tomi, Ruusalepp, Arno, Schadt, Eric E., Koplev, Simon, Björkegren, Johan L. M., Codoni, Veronica, Civelek, Mete, Smith, Nicholas L., Tregouet, David A., Christophersen, Ingrid E., Roselli, Carolina, Lubitz, Steven A., Ellinor, Patrick T., Tai, E. Shyong, Kooner, Jaspal S., Kato, Norihiro, He, Jiang, van der Harst, Pim, Elliott, Paul, Chambers, John C., Takeuchi, Fumihiko, Johnson, Andrew D., Sanghera, Dharambir K., Melander, Olle, Jern, Christina, Strbian, Daniel, Fernandez-Cadenas, Israel, Longstreth, W. T., Rolfs, Arndt, Hata, Jun, Woo, Daniel, Rosand, Jonathan, Pare, Guillaume, Hopewell, Jemma C., Saleheen, Danish, Stefansson, Kari, Worrall, Bradford B., Kittner, Steven J., Seshadri, Sudha, Fornage, Myriam, Markus, Hugh S., Howson, Joanna M. M., Kamatani, Yoichiro, Debette, Stephanie, Dichgans, Martin
में प्रकाशित Nat Genet (2018)