Sex-stratified gene regulatory networks reveal female key-driver genes of atherosclerosis involved in smooth muscle cell phenotype switching

BACKGROUND: While sex differences in coronary artery disease (CAD) are widely accepted with women developing more stable atherosclerosis than men, the underlying pathobiology of such differences remains largely unknown. In CAD, recent integrative systems biological studies have inferred gene regulat...

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書誌詳細
出版年:Circulation
主要な著者: Hartman, Robin J.G., Owsiany, Katie, Ma, Lijiang, Koplev, Simon, Hao, Ke, Slenders, Lotte, Civelek, Mete, Mokry, Michal, Kovacic, Jason C., Pasterkamp, Gerard, Owens, Gary, Björkegren, Johan L.M., den Ruijter, Hester M.
フォーマット: Artigo
言語:Inglês
出版事項: 2021
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7930467/
https://ncbi.nlm.nih.gov/pubmed/33499648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.120.051231
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