Sex-stratified gene regulatory networks reveal female key-driver genes of atherosclerosis involved in smooth muscle cell phenotype switching

BACKGROUND: While sex differences in coronary artery disease (CAD) are widely accepted with women developing more stable atherosclerosis than men, the underlying pathobiology of such differences remains largely unknown. In CAD, recent integrative systems biological studies have inferred gene regulat...

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Détails bibliographiques
Publié dans:Circulation
Auteurs principaux: Hartman, Robin J.G., Owsiany, Katie, Ma, Lijiang, Koplev, Simon, Hao, Ke, Slenders, Lotte, Civelek, Mete, Mokry, Michal, Kovacic, Jason C., Pasterkamp, Gerard, Owens, Gary, Björkegren, Johan L.M., den Ruijter, Hester M.
Format: Artigo
Langue:Inglês
Publié: 2021
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7930467/
https://ncbi.nlm.nih.gov/pubmed/33499648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.120.051231
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