Sex-stratified gene regulatory networks reveal female key-driver genes of atherosclerosis involved in smooth muscle cell phenotype switching

BACKGROUND: While sex differences in coronary artery disease (CAD) are widely accepted with women developing more stable atherosclerosis than men, the underlying pathobiology of such differences remains largely unknown. In CAD, recent integrative systems biological studies have inferred gene regulat...

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Bibliografski detalji
Izdano u:Circulation
Glavni autori: Hartman, Robin J.G., Owsiany, Katie, Ma, Lijiang, Koplev, Simon, Hao, Ke, Slenders, Lotte, Civelek, Mete, Mokry, Michal, Kovacic, Jason C., Pasterkamp, Gerard, Owens, Gary, Björkegren, Johan L.M., den Ruijter, Hester M.
Format: Artigo
Jezik:Inglês
Izdano: 2021
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7930467/
https://ncbi.nlm.nih.gov/pubmed/33499648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.120.051231
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