Intrinsic transcriptomic sex differences in human endothelial cells at birth and in adults are associated with coronary artery disease targets

Sex differences in endothelial cell (EC) biology may reflect intrinsic differences driven by chromosomes or sex steroid exposure and gender differences accumulated over life. We analysed EC gene expression data from boy–girl twins at birth and in non-twin adults to detect sex differences at differen...

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Pubblicato in:Sci Rep
Autori principali: Hartman, Robin J. G., Kapteijn, Daniek M. C., Haitjema, Saskia, Bekker, Mireille N., Mokry, Michal, Pasterkamp, Gerard, Civelek, Mete, den Ruijter, Hester M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7378217/
https://ncbi.nlm.nih.gov/pubmed/32704153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69451-8
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