Effect of Network Architecture on Synchronization and Entrainment Properties of the Circadian Oscillations in the Suprachiasmatic Nucleus

Autor Hafner, Marc, Koeppl, Heinz, Gonze, Didier
Vydáno 2012

Mapping behavioral specifications to model parameters in synthetic biology

Autor Koeppl, Heinz, Hafner, Marc, Lu, James
Vydáno 2013

Alternative drug sensitivity metrics improve preclinical cancer pharmacogenomics

Autor Hafner, Marc, Niepel, Mario, Sorger, Peter K.
Vydáno v Nat Biotechnol (2017)

‘Glocal’ Robustness Analysis and Model Discrimination for Circadian Oscillators

Autor Hafner, Marc, Koeppl, Heinz, Hasler, Martin, Wagner, Andreas
Vydáno 2009

Growth rate inhibition metrics correct for confounders in measuring sensitivity to cancer drugs

Autor Hafner, Marc, Niepel, Mario, Chung, Mirra, Sorger, Peter K.
Vydáno v Nat Methods (2016)

Measuring Cancer Drug Sensitivity and Resistance in Cultured Cells

Autor Niepel, Mario, Hafner, Marc, Chung, Mirra, Sorger, Peter K.
Vydáno v Curr Protoc Chem Biol (2017)

Designing drug response experiments and quantifying their results

Autor Hafner, Marc, Niepel, Mario, Subramanian, Kartik, Sorger, Peter K.
Vydáno v Curr Protoc Chem Biol (2017)

Efficient characterization of high-dimensional parameter spaces for systems biology

Autor Zamora-Sillero, Elías, Hafner, Marc, Ibig, Ariane, Stelling, Joerg, Wagner, Andreas
Vydáno 2011

A multitargeted probe-based strategy to identify signaling vulnerabilities in cancers

Autor Rao, Suman, Du, Guangyan, Hafner, Marc, Subramanian, Kartik, Sorger, Peter K., Gray, Nathanael S.
Vydáno v J Biol Chem (2019)

Fractional killing arises from cell-to-cell variability in overcoming a caspase activity threshold

Autor Roux, Jérémie, Hafner, Marc, Bandara, Samuel, Sims, Joshua J, Hudson, Hannah, Chai, Diana, Sorger, Peter K
Vydáno v Mol Syst Biol (2015)

Modular Design of Artificial Tissue Homeostasis: Robust Control through Synthetic Cellular Heterogeneity

Autor Miller, Miles, Hafner, Marc, Sontag, Eduardo, Davidsohn, Noah, Subramanian, Sairam, Purnick, Priscilla E. M., Lauffenburger, Douglas, Weiss, Ron
Vydáno 2012

Profiles of Basal and Stimulated Receptor Signaling Networks Predict Drug Response in Breast Cancer Lines

Autor Niepel, Mario, Hafner, Marc, Pace, Emily A., Chung, Mirra, Chai, Diana H., Zhou, Lili, Schoeberl, Birgit, Sorger, Peter K.
Vydáno 2013

Analysis of growth factor signaling in genetically diverse breast cancer lines

Autor Niepel, Mario, Hafner, Marc, Pace, Emily A, Chung, Mirra, Chai, Diana H, Zhou, Lili, Muhlich, Jeremy L, Schoeberl, Birgit, Sorger, Peter K
Vydáno v BMC Biol (2014)

GRcalculator: an online tool for calculating and mining dose–response data

Autor Clark, Nicholas A., Hafner, Marc, Kouril, Michal, Williams, Elizabeth H., Muhlich, Jeremy L., Pilarczyk, Marcin, Niepel, Mario, Sorger, Peter K., Medvedovic, Mario
Vydáno v BMC Cancer (2017)

Quantification of sensitivity and resistance of breast cancer cell lines to anti-cancer drugs using GR metrics

Autor Hafner, Marc, Heiser, Laura M., Williams, Elizabeth H., Niepel, Mario, Wang, Nicholas J., Korkola, James E., Gray, Joe W., Sorger, Peter K.
Vydáno v Sci Data (2017)

Cheminformatics tools for analyzing and designing optimized small molecule collections and libraries

Autor Moret, Nienke, Clark, Nicholas A., Hafner, Marc, Wang, Yuan, Lounkine, Eugen, Medvedovic, Mario, Wang, Jinhua, Gray, Nathanael, Jenkins, Jeremy, Sorger, Peter K.
Vydáno v Cell Chem Biol (2019)

Systems Approaches to Cancer Biology

Autor Archer, Tenley C., Fertig, Elana J., Gosline, Sara J.C., Hafner, Marc, Hughes, Shannon K., Joughin, Brian A., Meyer, Aaron S., Piccolo, Stephen R., Shajahan-Haq, Ayesha N.
Vydáno v Cancer Res (2016)

Multi-omics profiling establishes the polypharmacology of FDA Approved CDK4/6 inhibitors and the potential for differential clinical activity

Autor Hafner, Marc, Mills, Caitlin Elizabeth, Subramanian, Kartik, Chen, Chen, Chung, Mirra, Boswell, Sarah Ann, Everley, Robert A., Liu, Changchang, Walmsley, Charlotte Sanden, Juric, Dejan, Sorger, Peter Karl
Vydáno v Cell Chem Biol (2019)

Few-shot learning creates predictive models of drug response that translate from high-throughput screens to individual patients

Autor Ma, Jianzhu, Fong, Samson H., Luo, Yunan, Bakkenist, Christopher J., Shen, John Paul, Mourragui, Soufiane, Wessels, Lodewyk F. A., Hafner, Marc, Sharan, Roded, Peng, Jian, Ideker, Trey
Vydáno v Nat Cancer (2021)

Common and cell-type specific responses to anti-cancer drugs revealed by high throughput transcript profiling

Autor Niepel, Mario, Hafner, Marc, Duan, Qiaonan, Wang, Zichen, Paull, Evan O., Chung, Mirra, Lu, Xiaodong, Stuart, Joshua M., Golub, Todd R., Subramanian, Aravind, Ma’ayan, Avi, Sorger, Peter K.
Vydáno v Nat Commun (2017)