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‘Glocal’ Robustness Analysis and Model Discrimination for Circadian Oscillators

To characterize the behavior and robustness of cellular circuits with many unknown parameters is a major challenge for systems biology. Its difficulty rises exponentially with the number of circuit components. We here propose a novel analysis method to meet this challenge. Our method identifies the...

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Bibliographic Details
Main Authors: Hafner, Marc, Koeppl, Heinz, Hasler, Martin, Wagner, Andreas
Format: Artigo
Language:Inglês
Published: Public Library of Science 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758577/
https://ncbi.nlm.nih.gov/pubmed/19834597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000534
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