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Circuit topology and the evolution of robustness in two-gene circadian oscillators
Many parameters driving the behavior of biochemical circuits vary extensively and are thus not fine-tuned. Therefore, the topology of such circuits (the who-interacts-with-whom) is key to understanding their central properties. I here explore several hundred different topologies of a simple biochemi...
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2005
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1183445/ https://ncbi.nlm.nih.gov/pubmed/16087882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501094102 |
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