High-Resolution Molecular Characterization of 15q11-q13 Rearrangements by Array Comparative Genomic Hybridization (Array CGH) with Detection of Gene Dosage

Por Wang, Nicholas J., Liu, Dahai, Parokonny, Alexander S., Schanen, N. Carolyn
Publicado em 2004

MORPHOMETRIC SUBTYPING FOR A PANEL OF BREAST CANCER CELL LINES

Por Han, Ju, Chang, Hang, Fontenay, Gerald, Wang, Nicholas J., Gray, Joe W., Parvin, Bahram
Publicado em 2009

Autistic disorder associated with a paternally derived unbalanced translocation leading to duplication of chromosome 15pter-q13.2: a case report

Por Wu, David J, Wang, Nicholas J, Driscoll, Jennette, Dorrani, Naghmeh, Liu, Dahai, Sigman, Marian, Schanen, N Carolyn
Publicado em 2009

Chromosome 15q11-13 duplication syndrome brain reveals epigenetic alterations in gene expression not predicted from copy number

Por Hogart, Amber, Leung, Karen N., Wang, Nicholas J., Wu, David J., Driscoll, Jennette, Vallero, Roxanne O., Schanen, N. Carolyn, LaSalle, Janine M.
Publicado em 2008

Multiple forms of atypical rearrangements generating supernumerary derivative chromosome 15

Por Sigman Marian, Dorrani Naghmeh, Malone Barbara M, Driscoll Jennette, Thatcher Karen N, Parokonny Alexander S, Wang Nicholas J, LaSalle Janine M, Schanen N Carolyn
Publicado em 2008-01-01

Multiple forms of atypical rearrangements generating supernumerary derivative chromosome 15

Por Wang, Nicholas J, Parokonny, Alexander S, Thatcher, Karen N, Driscoll, Jennette, Malone, Barbara M, Dorrani, Naghmeh, Sigman, Marian, LaSalle, Janine M, Schanen, N Carolyn
Publicado em 2008

Patient-specific factors influence somatic variation patterns in von Hippel–Lindau disease renal tumours

Por Fei, Suzanne S., Mitchell, Asia D., Heskett, Michael B., Vocke, Cathy D., Ricketts, Christopher J., Peto, Myron, Wang, Nicholas J., Sönmez, Kemal, Linehan, W. Marston, Spellman, Paul T.
Publicado no Nat Commun (2016)

ARTIK-52 induces replication-dependent DNA damage and p53 activation exclusively in cells of prostate and breast cancer origin

Por Fleyshman, Daria, Cheney, Peter, Ströse, Anda, Mudambi, Shaila, Safina, Alfiya, Commane, Mairead, Purmal, Andrei, Morgan, Kelsey, Wang, Nicholas J., Gray, Joe, Spellman, Paul T., Issaeva, Natalia, Gurova, Katerina
Publicado no Cell Cycle (2015)

Exome Sequencing of Cell-Free DNA from Metastatic Cancer Patients Identifies Clinically Actionable Mutations Distinct from Primary Disease

Por Butler, Timothy M., Johnson-Camacho, Katherine, Peto, Myron, Wang, Nicholas J., Macey, Tara A., Korkola, James E., Koppie, Theresa M., Corless, Christopher L., Gray, Joe W., Spellman, Paul T.
Publicado no PLoS One (2015)

Analysis of molecular inversion probe performance for allele copy number determination

Por Wang, Yuker, Moorhead, Martin, Karlin-Neumann, George, Wang, Nicholas J, Ireland, James, Lin, Steven, Chen, Chunnuan, Heiser, Laura M, Chin, Koei, Esserman, Laura, Gray, Joe W, Spellman, Paul T, Faham, Malek
Publicado em 2007

Comparative analyses of gene copy number and mRNA expression in glioblastoma multiforme tumors and xenografts

Por Hodgson, J. Graeme, Yeh, Ru-Fang, Ray, Amrita, Wang, Nicholas J., Smirnov, Ivan, Yu, Mamie, Hariono, Sujatmi, Silber, Joachim, Feiler, Heidi S., Gray, Joe W., Spellman, Paul T., Vandenberg, Scott R., Berger, Mitchel S., James, C. David
Publicado em 2009

Xenografts faithfully recapitulate breast cancer-specific gene expression patterns of parent primary breast tumors

Por Petrillo, Laura A., Wolf, Denise M., Kapoun, Ann M., Wang, Nicholas J., Barczak, Andrea, Xiao, Yuanyuan, Korkaya, Hasan, Baehner, Frederick, Lewicki, John, Wicha, Max, Park, John W., Spellman, Paul T., Gray, Joe W., van't Veer, Laura, Esserman, Laura J.
Publicado em 2012

Integrated analysis of breast cancer cell lines reveals unique signaling pathways

Por Heiser, Laura M, Wang, Nicholas J, Talcott, Carolyn L, Laderoute, Keith R, Knapp, Merrill, Guan, Yinghui, Hu, Zhi, Ziyad, Safiyyah, Weber, Barbara L, Laquerre, Sylvie, Jackson, Jeffrey R, Wooster, Richard F, Kuo, Wen Lin, Gray, Joe W, Spellman, Paul T
Publicado em 2009

Cross-platform pathway-based analysis identifies markers of response to the PARP inhibitor olaparib

Por Daemen, Anneleen, Wolf, Denise M., Korkola, James E., Griffith, Obi L., Frankum, Jessica R., Brough, Rachel, Jakkula, Lakshmi R., Wang, Nicholas J., Natrajan, Rachael, Reis-Filho, Jorge S., Lord, Christopher J., Ashworth, Alan, Spellman, Paul T., Gray, Joe W., van’t Veer, Laura J.
Publicado em 2012

A systems analysis of the chemosensitivity of breast cancer cells to the polyamine analogue PG-11047

Por Kuo, Wen-Lin, Das, Debopriya, Ziyad, Safiyyah, Bhattacharya, Sanchita, Gibb, William J, Heiser, Laura M, Sadanandam, Anguraj, Fontenay, Gerald V, Hu, Zhi, Wang, Nicholas J, Bayani, Nora, Feiler, Heidi S, Neve, Richard M, Wyrobek, Andrew J, Spellman, Paul T, Marton, Laurence J, Gray, Joe W
Publicado em 2009

Cellular androgen content influences enzalutamide agonism of F877L mutant androgen receptor

Por Coleman, Daniel J., Van Hook, Kathryn, King, Carly J., Schwartzman, Jacob, Lisac, Robert, Urrutia, Joshua, Sehrawat, Archana, Woodward, Josha, Wang, Nicholas J., Gulati, Roman, Thomas, George V., Beer, Tomasz M., Gleave, Martin, Korkola, James E., Gao, Lina, Heiser, Laura M., Alumkal, Joshi J.
Publicado no Oncotarget (2016)

Decoupling of the PI3K Pathway via Mutation Necessitates Combinatorial Treatment in HER2+ Breast Cancer

Por Korkola, James E., Collisson, Eric A., Heiser, Laura, Oates, Chris, Bayani, Nora, Itani, Sleiman, Esch, Amanda, Thompson, Wallace, Griffith, Obi L., Wang, Nicholas J., Kuo, Wen-Lin, Cooper, Brian, Billig, Jessica, Ziyad, Safiyyah, Hung, Jenny L., Jakkula, Lakshmi, Feiler, Heidi, Lu, Yiling, Mills, Gordon B., Spellman, Paul T., Tomlin, Claire, Mukherjee, Sach, Gray, Joe W.
Publicado no PLoS One (2015)

A community effort to assess and improve drug sensitivity prediction algorithms

Por Costello, James C, Heiser, Laura M, Georgii, Elisabeth, Gönen, Mehmet, Menden, Michael P, Wang, Nicholas J, Bansal, Mukesh, Ammad-ud-din, Muhammad, Hintsanen, Petteri, Khan, Suleiman A, Mpindi, John-Patrick, Kallioniemi, Olli, Honkela, Antti, Aittokallio, Tero, Wennerberg, Krister, Collins, James J, Gallahan, Dan, Singer, Dinah, Saez-Rodriguez, Julio, Kaski, Samuel, Gray, Joe W, Stolovitzky, Gustavo
Publicado no Nat Biotechnol (2014)

Upregulation of ER signaling as an adaptive mechanism of cell survival in HER2-positive breast tumors treated with anti-HER2 therapy

Por Giuliano, Mario, Hu, Huizhong, Wang, Yen-Chao, Fu, Xiaoyong, Nardone, Agostina, Herrera, Sabrina, Mao, Sufeng, Contreras, Alejandro, Gutierrez, Carolina, Wang, Tao, Hilsenbeck, Susan G., De Angelis, Carmine, Wang, Nicholas J., Heiser, Laura M., Gray, Joe W., Lopez-Tarruella, Sara, Pavlick, Anne C., Trivedi, Meghana V., Chamness, Gary C., Chang, Jenny C., Osborne, C. Kent, Rimawi, Mothaffar F., Schiff, Rachel
Publicado no Clin Cancer Res (2015)

Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in the MAPK pathway

Por Shain, A. Hunter, Garrido, Maria, Botton, Thomas, Talevich, Eric, Yeh, Iwei, Sanborn, J. Zachary, Chung, Jongsuk, Wang, Nicholas J., Kakavand, Hojabr, Mann, Graham J., Thompson, John F., Wiesner, Thomas, Roy, Ritu, Olshen, Adam B., Gagnon, Alexander, Gray, Joe W., Huh, Nam, Hur, Joe S., Busam, Klaus J., Scolyer, Richard A., Cho, Raymond J., Murali, Rajmohan, Bastian, Boris C.
Publicado no Nat Genet (2015)