Towards personalized treatment for early stage HER2-positive breast cancer

by Goutsouliak, Kristina, Veeraraghavan, Jamunarani, Sethunath, Vidyalakshmi, De Angelis, Carmine, Osborne, C. Kent, Rimawi, Mothaffar F., Schiff, Rachel
Published in Nat Rev Clin Oncol (2019)

EGFR Expression in Breast Cancer Association with biologic phenotype and clinical outcomes

by Rimawi, Mothaffar F., Shetty, Priya B., Weiss, Heidi L., Schiff, Rachel, Osborne, C. Kent, Chamness, Gary C., Elledge, Richard M.
Published 2010

De-escalation of treatment in HER2-positive breast cancer: Determinants of response and mechanisms of resistance

by Veeraraghavan, Jamunarani, De Angelis, Carmine, Reis-Filho, Jorge S., Prat, Aleix, Rimawi, Mothaffar F., Pascual, Tomás, Osborne, C. Kent, Schiff, Rachel
Published in Breast (2017)

THERAPEUTIC POTENTIAL OF THE DUAL EGFR/HER2 INHIBITOR AZD8931 IN CIRCUMVENTING ENDOCRINE RESISTANCE

by Morrison, Gladys, Fu, Xiaoyong, Shea, Marty, Nanda, Sarmistha, Giuliano, Mario, Wang, Tao, Klinowska, Teresa, Osborne, C. Kent, Rimawi, Mothaffar F., Schiff, Rachel
Published 2014

Lumpectomy followed by radiation improves survival in HER2 positive and triple‐negative breast cancer with high tumor‐infiltrating lymphocytes compared to mastectomy alone

by Mouabbi, Jason A., Chand, Momal, Asghar, Ishaq A., Sakhi, Ramen, Ockner, Daniel, Dul, Carrie L., Hadid, Tarik, Aref, Amr, Rimawi, Mothaffar F., Hoyos, Valentina
Published in Cancer Med (2021)

β1 integrin mediates an alternative survival pathway in breast cancer cells resistant to lapatinib

by Huang, Catherine, Park, Catherine C, Hilsenbeck, Susan G, Ward, Robin, Rimawi, Mothaffar F, Wang, Yen-chao, Shou, Jiang, Bissell, Mina J, Osborne, C Kent, Schiff, Rachel
Published 2011

Reduced Dose and Intermittent Treatment with Lapatinib and Trastuzumab for Potent Blockade of the HER Pathway in HER-2/neu Overexpressing Breast Tumor Xenografts

by Rimawi, Mothaffar F., Wiechmann, Lisa S., Wang, Yen-Chao, Huang, Catherine, Migliaccio, Ilenia, Wu, Meng-Fen, Gutierrez, Carolina, Hilsenbeck, Susan G., Arpino, Grazia, Massarweh, Suleiman, Ward, Robin, Soliz, Robert, Osborne, C. Kent, Schiff, Rachel
Published 2010

High IGF-IR activity in triple-negative breast cancer cell lines and tumorgrafts correlates with sensitivity to anti-IGF-IR therapy

by Litzenburger, Beate C., Creighton, Chad J., Tsimelzon, Anna, Chan, Bonita T., Hilsenbeck, Susan G., Wang, Tao, Carboni, Joan M., Gottardis, Marco M., Huang, Fei, Chang, Jenny C., Lewis, Michael T., Rimawi, Mothaffar F., Lee, Adrian V.
Published 2010

Multicenter Phase II Study of Neoadjuvant Lapatinib and Trastuzumab With Hormonal Therapy and Without Chemotherapy in Patients With Human Epidermal Growth Factor Receptor 2–Overexp...

by Rimawi, Mothaffar F., Mayer, Ingrid A., Forero, Andres, Nanda, Rita, Goetz, Matthew P., Rodriguez, Angel A., Pavlick, Anne C., Wang, Tao, Hilsenbeck, Susan G., Gutierrez, Carolina, Schiff, Rachel, Osborne, C. Kent, Chang, Jenny C.
Published 2013

Different mechanisms for resistance to trastuzumab versus lapatinib in HER2- positive breast cancers -- role of estrogen receptor and HER2 reactivation

by Wang, Yen-Chao, Morrison, Gladys, Gillihan, Ryan, Guo, Jun, Ward, Robin M, Fu, Xiaoyong, Botero, Maria F, Healy, Nuala A, Hilsenbeck, Susan G, Phillips, Gail Lewis, Chamness, Gary C, Rimawi, Mothaffar F, Osborne, C Kent, Schiff, Rachel
Published 2011

Vitamin D Levels, Vitamin D Receptor Polymorphisms, and Inflammatory Cytokines in Aromatase Inhibitor-Induced Arthralgias: An Analysis of CCTG MA.27

by Niravath, Polly, Chen, Bingshu, Chapman, Judy-Anne W., Agarwal, Sandeep K., Welschhans, Robert L., Bongartz, Tim, Kalari, Krishna R., Shepherd, Lois E., Bartlett, John, Pritchard, Kathleen, Gelmon, Karen, Hilsenbeck, Susan G., Rimawi, Mothaffar F., Osborne, C. Kent, Goss, Paul E., Ingle, James N.
Published in Clin Breast Cancer (2017)

The oral selective oestrogen receptor degrader (SERD) AZD9496 is comparable to fulvestrant in antagonising ER and circumventing endocrine resistance

by Nardone, Agostina, Weir, Hazel, Delpuech, Oona, Brown, Henry, De Angelis, Carmine, Cataldo, Maria Letizia, Fu, Xiaoyong, Shea, Martin J., Mitchell, Tamika, Veeraraghavan, Jamunarani, Nagi, Chandandeep, Pilling, Mark, Rimawi, Mothaffar F., Trivedi, Meghana, Hilsenbeck, Susan G., Chamness, Gary C., Jeselsohn, Rinath, Osborne, C. Kent, Schiff, Rachel
Published in Br J Cancer (2018)

Neratinib plus trastuzumab is superior to pertuzumab plus trastuzumab in HER2-positive breast cancer xenograft models

by Veeraraghavan, Jamunarani, Gutierrez, Carolina, Sethunath, Vidyalakshmi, Mehravaran, Sepideh, Giuliano, Mario, Shea, Martin J., Mitchell, Tamika, Wang, Tao, Nanda, Sarmistha, Pereira, Resel, Davis, Robert, Goutsouliak, Kristina, Qin, Lanfang, De Angelis, Carmine, Diala, Irmina, Lalani, Alshad S., Nagi, Chandandeep, Hilsenbeck, Susan G., Rimawi, Mothaffar F., Osborne, C. Kent, Schiff, Rachel
Published in NPJ Breast Cancer (2021)

Spatial proximity to fibroblasts impacts molecular features and therapeutic sensitivity of breast cancer cells influencing clinical outcomes

by Marusyk, Andriy, Tabassum, Doris P., Janiszewska, Michalina, Place, Andrew E., Trinh, Anne, Rozhok, Andrii I., Pyne, Saumyadipta, Guerriero, Jennifer L., Shu, Shaokun, Ekram, Muhammad, Ishkin, Alexander, Cahill, Daniel P., Nikolsky, Yuri, Chan, Timothy A., Rimawi, Mothaffar F., Hilsenbeck, Susan, Schiff, Rachel, Osborne, Kent C., Letai, Antony, Polyak, Kornelia
Published in Cancer Res (2016)

Endocrine-Based Treatments in Clinically-Relevant Subgroups of Hormone Receptor-Positive/HER2-Negative Metastatic Breast Cancer: Systematic Review and Meta-Analysis

by Schettini, Francesco, Giuliano, Mario, Giudici, Fabiola, Conte, Benedetta, De Placido, Pietro, Venturini, Sergio, Rognoni, Carla, Di Leo, Angelo, Locci, Mariavittoria, Jerusalem, Guy, Del Mastro, Lucia, Puglisi, Fabio, Conte, PierFranco, De Laurentiis, Michelino, Pusztai, Lajos, Rimawi, Mothaffar F., Schiff, Rachel, Arpino, Grazia, De Placido, Sabino, Prat, Aleix, Generali, Daniele
Published in Cancers (Basel) (2021)

Phase II Study of Lapatinib in Combination With Trastuzumab in Patients With Human Epidermal Growth Factor Receptor 2–Positive Metastatic Breast Cancer: Clinical Outcomes and Predi...

by Lin, Nancy U., Guo, Hao, Yap, Jeffrey T., Mayer, Ingrid A., Falkson, Carla I., Hobday, Timothy J., Dees, E. Claire, Richardson, Andrea L., Nanda, Rita, Rimawi, Mothaffar F., Ryabin, Nicole, Najita, Julie S., Barry, William T., Arteaga, Carlos L., Wolff, Antonio C., Krop, Ian E., Winer, Eric P., Van den Abbeele, Annick D.
Published in J Clin Oncol (2015)

Chemotherapy for Isolated Locoregional Recurrence of Breast Cancer: The CALOR Randomised Trial

by Aebi, Stefan, Gelber, Shari, Anderson, Stewart J., Láng, István, Robidoux, André, Martín, Miguel, Nortier, Johan W.R., Paterson, Alexander H.G., Rimawi, Mothaffar F., Cañada, José Manuel Baena, Thürlimann, Beat, Murray, Elizabeth, Mamounas, Eleftherios P., Geyer, Charles E., Price, Karen N., Coates, Alan S., Gelber, Richard D., Rastogi, Priya, Wolmark, Norman, Wapnir, Irene L.
Published 2014

TBCRC 001: Randomized Phase II Study of Cetuximab in Combination With Carboplatin in Stage IV Triple-Negative Breast Cancer

by Carey, Lisa A., Rugo, Hope S., Marcom, P. Kelly, Mayer, Erica L., Esteva, Francisco J., Ma, Cynthia X., Liu, Minetta C., Storniolo, Anna Maria, Rimawi, Mothaffar F., Forero-Torres, Andres, Wolff, Antonio C., Hobday, Timothy J., Ivanova, Anastasia, Chiu, Wing-Keung, Ferraro, Madlyn, Burrows, Emily, Bernard, Philip S., Hoadley, Katherine A., Perou, Charles M., Winer, Eric P.
Published 2012

Efficacy of Chemotherapy for ER-Negative and ER-Positive Isolated Locoregional Recurrence of Breast Cancer: Final Analysis of the CALOR Trial

by Wapnir, Irene L., Price, Karen N., Anderson, Stewart J., Robidoux, André, Martín, Miguel, Nortier, Johan W.R., Paterson, Alexander H.G., Rimawi, Mothaffar F., Láng, István, Baena-Cañada, José Manuel, Thürlimann, Beat, Mamounas, Eleftherios P., Geyer, Charles E., Gelber, Shari, Coates, Alan S., Gelber, Richard D., Rastogi, Priya, Regan, Meredith M., Wolmark, Norman, Aebi, Stefan
Published in J Clin Oncol (2018)

Circulating and disseminated tumor cells from breast cancer patient-derived xenograft-bearing mice as a novel model to study metastasis

by Giuliano, Mario, Herrera, Sabrina, Christiny, Pavel, Shaw, Chad, Creighton, Chad J, Mitchell, Tamika, Bhat, Raksha, Zhang, Xiaomei, Mao, Sufeng, Dobrolecki, Lacey E, Al-rawi, Ahmed, Chen, Fengju, Veneziani, Bianca M, Zhang, Xiang H-F, Hilsenbeck, Susan G, Contreras, Alejandro, Gutierrez, Carolina, Jeselsohn, Rinath M, Rimawi, Mothaffar F, Osborne, C Kent, Lewis, Michael T, Schiff, Rachel, Trivedi, Meghana V
Published in Breast Cancer Res (2015)