The Changing Role of ER in Endocrine Resistance

per Nardone, Agostina, De Angelis, Carmine, Trivedi, Meghana V., Osborne, C. Kent, Schiff, Rachel
Publicat a Breast (2015)

Long-term cultures of stem/progenitor cells from lobular and ductal breast carcinomas under non-adherent conditions

per Nardone, Agostina, Corvigno, Sara, Brescia, Annalisa, D’Andrea, Daniel, Limite, Gennaro, Veneziani, Bianca Maria
Publicat 2010

Estrogen-induced transcription at individual alleles is independent of receptor level and active conformation but can be modulated by coactivators activity

per Stossi, Fabio, Dandekar, Radhika D, Mancini, Maureen G, Gu, Guowei, Fuqua, Suzanne A W, Nardone, Agostina, De Angelis, Carmine, Fu, Xiaoyong, Schiff, Rachel, Bedford, Mark T, Xu, Wei, Johansson, Hans E, Stephan, Clifford C, Mancini, Michael A
Publicat a Nucleic Acids Res (2020)

Circulating tumor cell investigation in breast cancer patient-derived xenograft models by automated immunofluorescence staining, image acquisition, and single cell retrieval and an...

per Ramirez, Arturo B., Bhat, Raksha, Sahay, Debashish, De Angelis, Carmine, Thangavel, Hariprasad, Hedayatpour, Sina, Dobrolecki, Lacey E., Nardone, Agostina, Giuliano, Mario, Nagi, Chandandeep, Rimawi, Mothaffar, Osborne, C. Kent, Lewis, Michael T., Stilwell, Jackie L., Kaldjian, Eric P., Schiff, Rachel, Trivedi, Meghana V.
Publicat a BMC Cancer (2019)

An epigenomic approach to therapy for tamoxifen-resistant breast cancer

per Feng, Qin, Zhang, Zheng, Shea, Martin J, Creighton, Chad J, Coarfa, Cristian, Hilsenbeck, Susan G, Lanz, Rainer, He, Bin, Wang, Lei, Fu, Xiaoyong, Nardone, Agostina, Song, Yongcheng, Bradner, James, Mitsiades, Nicholas, Mitsiades, Constantine S, Osborne, C Kent, Schiff, Rachel, O'Malley, Bert W
Publicat 2014

The oral selective oestrogen receptor degrader (SERD) AZD9496 is comparable to fulvestrant in antagonising ER and circumventing endocrine resistance

per Nardone, Agostina, Weir, Hazel, Delpuech, Oona, Brown, Henry, De Angelis, Carmine, Cataldo, Maria Letizia, Fu, Xiaoyong, Shea, Martin J., Mitchell, Tamika, Veeraraghavan, Jamunarani, Nagi, Chandandeep, Pilling, Mark, Rimawi, Mothaffar F., Trivedi, Meghana, Hilsenbeck, Susan G., Chamness, Gary C., Jeselsohn, Rinath, Osborne, C. Kent, Schiff, Rachel
Publicat a Br J Cancer (2018)

Pathway-Centric Integrative Analysis Identifies RRM2 as a Prognostic Marker in Breast Cancer Associated with Poor Survival and Tamoxifen Resistance()()()

per Putluri, Nagireddy, Maity, Suman, Kommangani, Ramakrishna, Creighton, Chad J., Putluri, Vasanta, Chen, Fengju, Nanda, Sarmishta, Bhowmik, Salil Kumar, Terunuma, Atsushi, Dorsey, Tiffany, Nardone, Agostina, Fu, Xiaoyong, Shaw, Chad, Sarkar, Tapasree Roy, Schiff, Rachel, Lydon, John P., O’Malley, Bert W., Ambs, Stefan, Das, Gokul M., Michailidis, George, Sreekumar, Arun
Publicat 2014

Embryonic transcription factor SOX9 drives breast cancer endocrine resistance

per Jeselsohn, Rinath, Cornwell, MacIntosh, Pun, Matthew, Buchwalter, Gilles, Nguyen, Mai, Bango, Clyde, Huang, Ying, Kuang, Yanan, Paweletz, Cloud, Fu, Xiaoyong, Nardone, Agostina, De Angelis, Carmine, Detre, Simone, Dodson, Andrew, Mohammed, Hisham, Carroll, Jason S., Bowden, Michaela, Rao, Prakash, Long, Henry W., Li, Fugen, Dowsett, Mitchell, Schiff, Rachel, Brown, Myles
Publicat a Proc Natl Acad Sci U S A (2017)

A CTC-Cluster-Specific Signature Derived from OMICS Analysis of Patient-Derived Xenograft Tumors Predicts Outcomes in Basal-Like Breast Cancer

per Thangavel, Hariprasad, Angelis, Carmine De, Vasaikar, Suhas, Bhat, Raksha, Jolly, Mohit Kumar, Nagi, Chandandeep, Creighton, Chad J., Chen, Fengju, Dobrolecki, Lacey E., George, Jason T., Kumar, Tanya, Abdulkareem, Noor Mazin, Mao, Sufeng, Nardone, Agostina, Rimawi, Mothaffar, Osborne, C. Kent, Lewis, Michael T., Levine, Herbert, Zhang, Bing, Schiff, Rachel, Giuliano, Mario, Trivedi, Meghana V.
Publicat a J Clin Med (2019)

Upregulation of ER signaling as an adaptive mechanism of cell survival in HER2-positive breast tumors treated with anti-HER2 therapy

per Giuliano, Mario, Hu, Huizhong, Wang, Yen-Chao, Fu, Xiaoyong, Nardone, Agostina, Herrera, Sabrina, Mao, Sufeng, Contreras, Alejandro, Gutierrez, Carolina, Wang, Tao, Hilsenbeck, Susan G., De Angelis, Carmine, Wang, Nicholas J., Heiser, Laura M., Gray, Joe W., Lopez-Tarruella, Sara, Pavlick, Anne C., Trivedi, Meghana V., Chamness, Gary C., Chang, Jenny C., Osborne, C. Kent, Rimawi, Mothaffar F., Schiff, Rachel
Publicat a Clin Cancer Res (2015)

Allele-specific chromatin recruitment and therapeutic vulnerabilities of ESR1 activating mutations

per Jeselsohn, Rinath, Bergholz, Johann S, Pun, Matthew, Cornwell, MacIntosh, Liu, Weihan, Nardone, Agostina, Xiao, Tengfei, Li, Wei, Qiu, Xintao, Buchwalter, Gilles, Feiglin, Ariel, Abell-Hart, Kayley, Fei, Teng, Rao, Prakash, Long, Henry, Kwiatkowski, Nicholas, Zhang, Tinghu, Gray, Nathanael, Melchers, Diane, Houtman, Rene, Liu, X. Shirley, Cohen, Ofir, Wagle, Nikhil, Winer, Eric P., Zhao, Jean, Brown, Myles
Publicat a Cancer Cell (2018)

FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer

per Fu, Xiaoyong, Pereira, Resel, De Angelis, Carmine, Veeraraghavan, Jamunarani, Nanda, Sarmistha, Qin, Lanfang, Cataldo, Maria L., Sethunath, Vidyalakshmi, Mehravaran, Sepideh, Gutierrez, Carolina, Chamness, Gary C., Feng, Qin, O’Malley, Bert W., Selenica, Pier, Weigelt, Britta, Reis-Filho, Jorge S., Cohen, Ofir, Wagle, Nikhil, Nardone, Agostina, Jeselsohn, Rinath, Brown, Myles, Rimawi, Mothaffar F., Osborne, C. Kent, Schiff, Rachel
Publicat a Proc Natl Acad Sci U S A (2019)

Targeting the mevalonate pathway to overcome acquired anti-HER2 treatment resistance in breast cancer

per Sethunath, Vidyalakshmi, Hu, Huizhong, Angelis, Carmine De, Veeraraghavan, Jamunarani, Qin, Lanfang, Wang, Nicholas, Simon, Lukas M., Wang, Tao, Fu, Xiaoyong, Nardone, Agostina, Pereira, Resel, Nanda, Sarmistha, Griffith, Obi L., Tsimelzon, Anna, Shaw, Chad, Chamness, Gary C., Reis-Filho, Jorge S., Weigelt, Britta, Heiser, Laura M., Hilsenbeck, Susan G., Huang, Shixia, Rimawi, Mothaffar F., Gray, Joe W., Osborne, C. Kent, Schiff, Rachel
Publicat a Mol Cancer Res (2019)

FOXA1 overexpression mediates endocrine resistance by altering the ER transcriptome and IL-8 expression in ER-positive breast cancer

per Fu, Xiaoyong, Jeselsohn, Rinath, Pereira, Resel, Hollingsworth, Emporia F., Creighton, Chad J., Li, Fugen, Shea, Martin, Nardone, Agostina, De Angelis, Carmine, Heiser, Laura M., Anur, Pavana, Wang, Nicholas, Grasso, Catherine S., Spellman, Paul T., Griffith, Obi L., Tsimelzon, Anna, Gutierrez, Carolina, Huang, Shixia, Edwards, Dean P., Trivedi, Meghana V., Rimawi, Mothaffar F., Lopez-Terrada, Dolores, Hilsenbeck, Susan G., Gray, Joe W., Brown, Myles, Osborne, C. Kent, Schiff, Rachel
Publicat a Proc Natl Acad Sci U S A (2016)

Overcoming endocrine resistance due to reduced PTEN levels in estrogen receptor-positive breast cancer by co-targeting mammalian target of rapamycin, protein kinase B, or mitogen-a...

per Fu, Xiaoyong, Creighton, Chad J, Biswal, Nrusingh C, Kumar, Vijetha, Shea, Martin, Herrera, Sabrina, Contreras, Alejandro, Gutierrez, Carolina, Wang, Tao, Nanda, Sarmistha, Giuliano, Mario, Morrison, Gladys, Nardone, Agostina, Karlin, Kristen L, Westbrook, Thomas F, Heiser, Laura M, Anur, Pavana, Spellman, Paul, Guichard, Sylvie M, Smith, Paul D, Davies, Barry R, Klinowska, Teresa, Lee, Adrian V, Mills, Gordon B, Rimawi, Mothaffar F, Hilsenbeck, Susan G, Gray, Joe W, Joshi, Amit, Osborne, C Kent, Schiff, Rachel
Publicat a Breast Cancer Res (2014)

HER2 Reactivation through Acquisition of the HER2 L755S Mutation as a Mechanism of Acquired Resistance to HER2-targeted Therapy in HER2+ Breast Cancer

per Xu, Xiaowei, De Angelis, Carmine, Burke, Kathleen A., Nardone, Agostina, Hu, Huizhong, Qin, Lanfang, Veeraraghavan, Jamunarani, Sethunath, Vidyalakshmi, Heiser, Laura M., Wang, Nicholas, Ng, Charlotte K.Y., Chen, Edward S., Renwick, Alexander, Wang, Tao, Nanda, Sarmistha, Shea, Martin, Mitchell, Tamika, Rajendran, Mahitha, Waters, Ian, Zabransky, Daniel J., Scott, Kenneth L., Gutierrez, Carolina, Nagi, Chandandeep, Geyer, Felipe C., Chamness, Gary C., Park, Ben H., Shaw, Chad A., Hilsenbeck, Susan G., Rimawi, Mothaffar F., Gray, Joe W., Weigelt, Britta, Reis-Filho, Jorge S., Osborne, C. Kent, Schiff, Rachel
Publicat a Clin Cancer Res (2017)