Genomic Determinants of PI3K Pathway Inhibitor Response in Cancer

Por Weigelt, Britta, Downward, Julian
Publicado em 2012

Unraveling the microenvironmental influences on the normal mammary gland and breast cancer

Por Weigelt, Britta, Bissell, Mina J.
Publicado em 2008

Molecular profiling currently offers no more than tumour morphology and basic immunohistochemistry

Por Weigelt, Britta, Reis-Filho, Jorge S
Publicado em 2010

The need for complex 3D culture models to unravel novel pathways and identify accurate biomarkers in breast cancer

Por Weigelt, Britta, Ghajar, Cyrus M, Bissell, Mina J
Publicado em 2014

Prognostic signatures in breast cancer: correlation does not imply causation

Por Ng, Charlotte, Weigelt, Britta, Grigoriadis, Anita, Reis-Filho, Jorge S
Publicado em 2012

Microarrays in the 2010s: the contribution of microarray-based gene expression profiling to breast cancer classification, prognostication and prediction

Por Colombo, Pierre-Emmanuel, Milanezi, Fernanda, Weigelt, Britta, Reis-Filho, Jorge S
Publicado em 2011

HER2 signaling pathway activation and response of breast cancer cells to HER2-targeting agents is dependent strongly on the 3D microenvironment

Por Weigelt, Britta, Lo, Alvin T., Park, Catherine C., Gray, Joe W., Bissell, Mina J.
Publicado em 2009

PI3K pathway dependencies in endometrioid endometrial cancer cell lines

Por Weigelt, Britta, Warne, Patricia H, Lambros, Maryou B, Reis-Filho, Jorge S, Downward, Julian
Publicado em 2013

Breast cancer intra-tumor heterogeneity

Por Martelotto, Luciano G, Ng, Charlotte KY, Piscuoglio, Salvatore, Weigelt, Britta, Reis-Filho, Jorge S
Publicado em 2014

The genomic heterogeneity of FIGO grade 3 endometrioid carcinoma: impacts on diagnostic accuracy and reproducibility

Por Hussein, Yaser R, Broaddus, Russell, Weigelt, Britta, Levine, Douglas A, Soslow, Robert A
Publicado no Int J Gynecol Pathol (2016)

Synthetic lethality of PARP inhibition in cancers lacking BRCA1 and BRCA2 mutations

Por Dedes, Konstantin J, Wilkerson, Paul M, Wetterskog, Daniel, Weigelt, Britta, Ashworth, Alan, Reis-Filho, Jorge S
Publicado em 2011

Absence of microsatellite instability in mucinous carcinomas of the breast

Por Lacroix-Triki, Magali, Lambros, Maryou B, Geyer, Felipe C, Suarez, Paula H, Reis-Filho, Jorge S, Weigelt, Britta
Publicado em 2010

Gene expression profiles of primary breast tumors maintained in distant metastases

Por Weigelt, Britta, Glas, Annuska M., Wessels, Lodewyk F. A., Witteveen, Anke T., Peterse, Johannes L., van't Veer, Laura J.
Publicado em 2003

Gene expression profiling and histopathological characterization of triple-negative/basal-like breast carcinomas

Por Kreike, Bas, van Kouwenhove, Marieke, Horlings, Hugo, Weigelt, Britta, Peterse, Hans, Bartelink, Harry, van de Vijver, Marc J
Publicado em 2007

Predictive performance of microarray gene signatures: impact of tumor heterogeneity and multiple mechanisms of drug resistance

Por Ng, Charlotte K. Y., Weigelt, Britta, A’Hern, Roger, Bidard, Francois-Clement, Lemetre, Christophe, Swanton, Charles, Shen, Ronglai, Reis-Filho, Jorge S.
Publicado em 2014

Microarray-Based Class Discovery for Molecular Classification of Breast Cancer: Analysis of Interobserver Agreement

Por Mackay, Alan, Weigelt, Britta, Grigoriadis, Anita, Kreike, Bas, Natrajan, Rachael, A’Hern, Roger, Tan, David S.P., Dowsett, Mitch, Ashworth, Alan, Reis-Filho, Jorge S.
Publicado em 2011

Determination of synthetic lethal interactions in KRAS oncogene-dependent cancer cells reveals novel therapeutic targeting strategies

Por Steckel, Michael, Molina-Arcas, Miriam, Weigelt, Britta, Marani, Michaela, Warne, Patricia H, Kuznetsov, Hanna, Kelly, Gavin, Saunders, Becky, Howell, Michael, Downward, Julian, Hancock, David C
Publicado em 2012

Benchmarking mutation effect prediction algorithms using functionally validated cancer-related missense mutations

Por Martelotto, Luciano G, Ng, Charlotte KY, De Filippo, Maria R, Zhang, Yan, Piscuoglio, Salvatore, Lim, Raymond S, Shen, Ronglai, Norton, Larry, Reis-Filho, Jorge S, Weigelt, Britta
Publicado no Genome Biol (2014)

Association between Morphologic CT Imaging Traits and Prognostically Relevant Gene Signatures in Women with High-Grade Serous Ovarian Cancer: A Hypothesis-generating Study

Por Vargas, Hebert Alberto, Miccò, Maura, Hong, Seong Im, Goldman, Debra A., Dao, Fanny, Weigelt, Britta, Soslow, Robert A., Hricak, Hedvig, Levine, Douglas A., Sala, Evis
Publicado no Radiology (2015)

SF3B1 mutations constitute a novel therapeutic target in breast cancer

Por Maguire, Sarah L, Leonidou, Andri, Wai, Patty, Marchiò, Caterina, Ng, Charlotte KY, Sapino, Anna, Salomon, Anne-Vincent, Reis-Filho, Jorge S, Weigelt, Britta, Natrajan, Rachael C
Publicado no J Pathol (2015)