THERAPEUTIC POTENTIAL OF THE DUAL EGFR/HER2 INHIBITOR AZD8931 IN CIRCUMVENTING ENDOCRINE RESISTANCE

by Morrison, Gladys, Fu, Xiaoyong, Shea, Marty, Nanda, Sarmistha, Giuliano, Mario, Wang, Tao, Klinowska, Teresa, Osborne, C. Kent, Rimawi, Mothaffar F., Schiff, Rachel
Published 2014

Sub-100 nm Gold Nanomatryoshkas Improve Photo-thermal Therapy Efficacy in Large and Highly Aggressive Triple Negative Breast Tumors

by Ayala-Orozco, Ciceron, Urban, Cordula, Bishnoi, Sandra, Urban, Alexander, Charron, Heather, Mitchell, Tamika, Shea, Martin, Nanda, Sarmistha, Schiff, Rachel, Halas, Naomi, Joshi, Amit
Published 2014

A novel role of ADGRF1 (GPR110) in promoting cellular quiescence and chemoresistance in human epidermal growth factor receptor 2-positive breast cancer

by Abdulkareem, Noor Mazin, Bhat, Raksha, Qin, Lanfang, Vasaikar, Suhas, Gopinathan, Ambily, Mitchell, Tamika, Shea, Martin J., Nanda, Sarmistha, Thangavel, Hariprasad, Zhang, Bing, De Angelis, Carmine, Schiff, Rachel, Trivedi, Meghana V.
Published in FASEB J (2021)

Au Nanomatryoshkas as Efficient Near-Infrared Photothermal Transducers for Cancer Treatment: Benchmarking against Nanoshells

by Ayala-Orozco, Ciceron, Urban, Cordula, Knight, Mark W., Urban, Alexander Skyrme, Neumann, Oara, Bishnoi, Sandra W., Mukherjee, Shaunak, Goodman, Amanda M., Charron, Heather, Mitchell, Tamika, Shea, Martin, Roy, Ronita, Nanda, Sarmistha, Schiff, Rachel, Halas, Naomi J., Joshi, Amit
Published 2014

GPCRs profiling and identification of GPR110 as a potential new target in HER2+ breast cancer

by Bhat, Raksha R., Yadav, Puja, Sahay, Debashish, Bhargava, Dharmendra K., Creighton, Chad J., Yazdanfard, Sahar, Al-rawi, Ahmed, Yadav, Vikas, Qin, Lanfang, Nanda, Sarmistha, Sethunath, Vidyalakshmi, Fu, Xiaoyong, De Angelis, Carmine, Narkar, Vihang A., Kent Osborne, C., Schiff, Rachel, Trivedi, Meghana V.
Published in Breast Cancer Res Treat (2018)

Neratinib plus trastuzumab is superior to pertuzumab plus trastuzumab in HER2-positive breast cancer xenograft models

by Veeraraghavan, Jamunarani, Gutierrez, Carolina, Sethunath, Vidyalakshmi, Mehravaran, Sepideh, Giuliano, Mario, Shea, Martin J., Mitchell, Tamika, Wang, Tao, Nanda, Sarmistha, Pereira, Resel, Davis, Robert, Goutsouliak, Kristina, Qin, Lanfang, De Angelis, Carmine, Diala, Irmina, Lalani, Alshad S., Nagi, Chandandeep, Hilsenbeck, Susan G., Rimawi, Mothaffar F., Osborne, C. Kent, Schiff, Rachel
Published in NPJ Breast Cancer (2021)

FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer

by Fu, Xiaoyong, Pereira, Resel, De Angelis, Carmine, Veeraraghavan, Jamunarani, Nanda, Sarmistha, Qin, Lanfang, Cataldo, Maria L., Sethunath, Vidyalakshmi, Mehravaran, Sepideh, Gutierrez, Carolina, Chamness, Gary C., Feng, Qin, O’Malley, Bert W., Selenica, Pier, Weigelt, Britta, Reis-Filho, Jorge S., Cohen, Ofir, Wagle, Nikhil, Nardone, Agostina, Jeselsohn, Rinath, Brown, Myles, Rimawi, Mothaffar F., Osborne, C. Kent, Schiff, Rachel
Published in Proc Natl Acad Sci U S A (2019)

Targeting the mevalonate pathway to overcome acquired anti-HER2 treatment resistance in breast cancer

by Sethunath, Vidyalakshmi, Hu, Huizhong, Angelis, Carmine De, Veeraraghavan, Jamunarani, Qin, Lanfang, Wang, Nicholas, Simon, Lukas M., Wang, Tao, Fu, Xiaoyong, Nardone, Agostina, Pereira, Resel, Nanda, Sarmistha, Griffith, Obi L., Tsimelzon, Anna, Shaw, Chad, Chamness, Gary C., Reis-Filho, Jorge S., Weigelt, Britta, Heiser, Laura M., Hilsenbeck, Susan G., Huang, Shixia, Rimawi, Mothaffar F., Gray, Joe W., Osborne, C. Kent, Schiff, Rachel
Published in Mol Cancer Res (2019)

Overcoming endocrine resistance due to reduced PTEN levels in estrogen receptor-positive breast cancer by co-targeting mammalian target of rapamycin, protein kinase B, or mitogen-a...

by Fu, Xiaoyong, Creighton, Chad J, Biswal, Nrusingh C, Kumar, Vijetha, Shea, Martin, Herrera, Sabrina, Contreras, Alejandro, Gutierrez, Carolina, Wang, Tao, Nanda, Sarmistha, Giuliano, Mario, Morrison, Gladys, Nardone, Agostina, Karlin, Kristen L, Westbrook, Thomas F, Heiser, Laura M, Anur, Pavana, Spellman, Paul, Guichard, Sylvie M, Smith, Paul D, Davies, Barry R, Klinowska, Teresa, Lee, Adrian V, Mills, Gordon B, Rimawi, Mothaffar F, Hilsenbeck, Susan G, Gray, Joe W, Joshi, Amit, Osborne, C Kent, Schiff, Rachel
Published in Breast Cancer Res (2014)

HER2 Reactivation through Acquisition of the HER2 L755S Mutation as a Mechanism of Acquired Resistance to HER2-targeted Therapy in HER2+ Breast Cancer

by Xu, Xiaowei, De Angelis, Carmine, Burke, Kathleen A., Nardone, Agostina, Hu, Huizhong, Qin, Lanfang, Veeraraghavan, Jamunarani, Sethunath, Vidyalakshmi, Heiser, Laura M., Wang, Nicholas, Ng, Charlotte K.Y., Chen, Edward S., Renwick, Alexander, Wang, Tao, Nanda, Sarmistha, Shea, Martin, Mitchell, Tamika, Rajendran, Mahitha, Waters, Ian, Zabransky, Daniel J., Scott, Kenneth L., Gutierrez, Carolina, Nagi, Chandandeep, Geyer, Felipe C., Chamness, Gary C., Park, Ben H., Shaw, Chad A., Hilsenbeck, Susan G., Rimawi, Mothaffar F., Gray, Joe W., Weigelt, Britta, Reis-Filho, Jorge S., Osborne, C. Kent, Schiff, Rachel
Published in Clin Cancer Res (2017)