Breast adenocarcinoma recurring as small cell carcinoma in a patient with a germline BRCA2 mutation: clonal evolution unchecked

Por Niravath, Polly, Eble, Tanya, Contreras, Alejandro, Li, Marilyn, Franco, Luis M, Rimawi, Mothaffar
Publicado no Exp Hematol Oncol (2015)

A Phase II Trial of Capecitabine Concomitantly With Whole-Brain Radiotherapy Followed by Capecitabine and Sunitinib for Brain Metastases From Breast Cancer

Por Niravath, Polly, Tham, Yee Lu, Wang, Tao, Rodriguez, Angel, Foreman, Claudette, Hilsenbeck, Susan G., Elledge, Richard, Rimawi, Mothaffar
Publicado no Oncologist (2015)

EGFR Expression in Breast Cancer Association with biologic phenotype and clinical outcomes

Por Rimawi, Mothaffar F., Shetty, Priya B., Weiss, Heidi L., Schiff, Rachel, Osborne, C. Kent, Chamness, Gary C., Elledge, Richard M.
Publicado em 2010

THERAPEUTIC POTENTIAL OF THE DUAL EGFR/HER2 INHIBITOR AZD8931 IN CIRCUMVENTING ENDOCRINE RESISTANCE

Por Morrison, Gladys, Fu, Xiaoyong, Shea, Marty, Nanda, Sarmistha, Giuliano, Mario, Wang, Tao, Klinowska, Teresa, Osborne, C. Kent, Rimawi, Mothaffar F., Schiff, Rachel
Publicado em 2014

Population pharmacokinetics of trastuzumab emtansine (T-DM1), a HER2-targeted antibody–drug conjugate, in patients with HER2-positive metastatic breast cancer: clinical implication...

Por Lu, Dan, Girish, Sandhya, Gao, Yuying, Wang, Bei, Yi, Joo-Hee, Guardino, Ellie, Samant, Meghna, Cobleigh, Melody, Rimawi, Mothaffar, Conte, Pierfranco, Jin, Jin Yan
Publicado em 2014

β1 integrin mediates an alternative survival pathway in breast cancer cells resistant to lapatinib

Por Huang, Catherine, Park, Catherine C, Hilsenbeck, Susan G, Ward, Robin, Rimawi, Mothaffar F, Wang, Yen-chao, Shou, Jiang, Bissell, Mina J, Osborne, C Kent, Schiff, Rachel
Publicado em 2011

A phase II neoadjuvant trial of anastrozole, fulvestrant and gefitinib in patients with newly diagnosed estrogen receptor positive breast cancer

Por Massarweh, Suleiman, Tham, Yee L, Huang, Jian, Sexton, Krystal, Weiss, Heidi, Tsimelzon, Anna, Bayer, Amanda, Rimawi, Mothaffar, Cai, Wei Yen, Hilsenbeck, Susan, Fuqua, Suzanne, Elledge, Richard
Publicado no Breast Cancer Res Treat (2011)

Upregulation of Mucin4 in ER-positive/HER2-Overexpressing Breast Cancer Xenografts with Acquired Resistance to Endocrine and HER2-Targeted Therapies

Por Chen, Albert C., Migliaccio, Ilenia, Rimawi, Mothaffar, Lopez-Tarruella, Sara, Creighton, Chad J., Massarweh, Suleiman, Huang, Catherine, Wang, Yen-Chao, Batra, Surinder K., Gutierrez, M. Carolina, Osborne, C. Kent, Schiff, Rachel
Publicado em 2012

Reduced Dose and Intermittent Treatment with Lapatinib and Trastuzumab for Potent Blockade of the HER Pathway in HER-2/neu Overexpressing Breast Tumor Xenografts

Por Rimawi, Mothaffar F., Wiechmann, Lisa S., Wang, Yen-Chao, Huang, Catherine, Migliaccio, Ilenia, Wu, Meng-Fen, Gutierrez, Carolina, Hilsenbeck, Susan G., Arpino, Grazia, Massarweh, Suleiman, Ward, Robin, Soliz, Robert, Osborne, C. Kent, Schiff, Rachel
Publicado em 2010

High IGF-IR activity in triple-negative breast cancer cell lines and tumorgrafts correlates with sensitivity to anti-IGF-IR therapy

Por Litzenburger, Beate C., Creighton, Chad J., Tsimelzon, Anna, Chan, Bonita T., Hilsenbeck, Susan G., Wang, Tao, Carboni, Joan M., Gottardis, Marco M., Huang, Fei, Chang, Jenny C., Lewis, Michael T., Rimawi, Mothaffar F., Lee, Adrian V.
Publicado em 2010

Multicenter Phase II Study of Neoadjuvant Lapatinib and Trastuzumab With Hormonal Therapy and Without Chemotherapy in Patients With Human Epidermal Growth Factor Receptor 2–Overexp...

Por Rimawi, Mothaffar F., Mayer, Ingrid A., Forero, Andres, Nanda, Rita, Goetz, Matthew P., Rodriguez, Angel A., Pavlick, Anne C., Wang, Tao, Hilsenbeck, Susan G., Gutierrez, Carolina, Schiff, Rachel, Osborne, C. Kent, Chang, Jenny C.
Publicado em 2013

Loss of Phosphatase and Tensin Homolog or Phosphoinositol-3 Kinase Activation and Response to Trastuzumab or Lapatinib in Human Epidermal Growth Factor Receptor 2–Overexpressing Lo...

Por Dave, Bhuvanesh, Migliaccio, Ilenia, Gutierrez, M. Carolina, Wu, Meng-Fen, Chamness, Gary C., Wong, Helen, Narasanna, Archana, Chakrabarty, Anindita, Hilsenbeck, Susan G., Huang, Jian, Rimawi, Mothaffar, Schiff, Rachel, Arteaga, Carlos, Osborne, C. Kent, Chang, Jenny C.
Publicado em 2011

Different mechanisms for resistance to trastuzumab versus lapatinib in HER2- positive breast cancers -- role of estrogen receptor and HER2 reactivation

Por Wang, Yen-Chao, Morrison, Gladys, Gillihan, Ryan, Guo, Jun, Ward, Robin M, Fu, Xiaoyong, Botero, Maria F, Healy, Nuala A, Hilsenbeck, Susan G, Phillips, Gail Lewis, Chamness, Gary C, Rimawi, Mothaffar F, Osborne, C Kent, Schiff, Rachel
Publicado em 2011

Phase IB Randomized, Double-Blinded, Placebo-Controlled, Dose Escalation Study of Polyphenon E in Women with Hormone Receptor-Negative Breast Cancer

Por Crew, Katherine D., Brown, Powel, Greenlee, Heather, Bevers, Therese B., Arun, Banu, Hudis, Clifford, McArthur, Heather L., Chang, Jenny, Rimawi, Mothaffar, Vornik, Lana, Cornelison, Terri L., Wang, Antai, Hibshoosh, Hanina, Ahmed, Aqeel, Terry, Mary Beth, Santella, Regina M., Lippman, Scott M., Hershman, Dawn L.
Publicado em 2012

Spatial proximity to fibroblasts impacts molecular features and therapeutic sensitivity of breast cancer cells influencing clinical outcomes

Por Marusyk, Andriy, Tabassum, Doris P., Janiszewska, Michalina, Place, Andrew E., Trinh, Anne, Rozhok, Andrii I., Pyne, Saumyadipta, Guerriero, Jennifer L., Shu, Shaokun, Ekram, Muhammad, Ishkin, Alexander, Cahill, Daniel P., Nikolsky, Yuri, Chan, Timothy A., Rimawi, Mothaffar F., Hilsenbeck, Susan, Schiff, Rachel, Osborne, Kent C., Letai, Antony, Polyak, Kornelia
Publicado no Cancer Res (2016)

Phase II Study of Lapatinib in Combination With Trastuzumab in Patients With Human Epidermal Growth Factor Receptor 2–Positive Metastatic Breast Cancer: Clinical Outcomes and Predi...

Por Lin, Nancy U., Guo, Hao, Yap, Jeffrey T., Mayer, Ingrid A., Falkson, Carla I., Hobday, Timothy J., Dees, E. Claire, Richardson, Andrea L., Nanda, Rita, Rimawi, Mothaffar F., Ryabin, Nicole, Najita, Julie S., Barry, William T., Arteaga, Carlos L., Wolff, Antonio C., Krop, Ian E., Winer, Eric P., Van den Abbeele, Annick D.
Publicado no J Clin Oncol (2015)

Chemotherapy for Isolated Locoregional Recurrence of Breast Cancer: The CALOR Randomised Trial

Por Aebi, Stefan, Gelber, Shari, Anderson, Stewart J., Láng, István, Robidoux, André, Martín, Miguel, Nortier, Johan W.R., Paterson, Alexander H.G., Rimawi, Mothaffar F., Cañada, José Manuel Baena, Thürlimann, Beat, Murray, Elizabeth, Mamounas, Eleftherios P., Geyer, Charles E., Price, Karen N., Coates, Alan S., Gelber, Richard D., Rastogi, Priya, Wolmark, Norman, Wapnir, Irene L.
Publicado em 2014

TBCRC 001: Randomized Phase II Study of Cetuximab in Combination With Carboplatin in Stage IV Triple-Negative Breast Cancer

Por Carey, Lisa A., Rugo, Hope S., Marcom, P. Kelly, Mayer, Erica L., Esteva, Francisco J., Ma, Cynthia X., Liu, Minetta C., Storniolo, Anna Maria, Rimawi, Mothaffar F., Forero-Torres, Andres, Wolff, Antonio C., Hobday, Timothy J., Ivanova, Anastasia, Chiu, Wing-Keung, Ferraro, Madlyn, Burrows, Emily, Bernard, Philip S., Hoadley, Katherine A., Perou, Charles M., Winer, Eric P.
Publicado em 2012

Circulating and disseminated tumor cells from breast cancer patient-derived xenograft-bearing mice as a novel model to study metastasis

Por Giuliano, Mario, Herrera, Sabrina, Christiny, Pavel, Shaw, Chad, Creighton, Chad J, Mitchell, Tamika, Bhat, Raksha, Zhang, Xiaomei, Mao, Sufeng, Dobrolecki, Lacey E, Al-rawi, Ahmed, Chen, Fengju, Veneziani, Bianca M, Zhang, Xiang H-F, Hilsenbeck, Susan G, Contreras, Alejandro, Gutierrez, Carolina, Jeselsohn, Rinath M, Rimawi, Mothaffar F, Osborne, C Kent, Lewis, Michael T, Schiff, Rachel, Trivedi, Meghana V
Publicado no Breast Cancer Res (2015)

Upregulation of ER signaling as an adaptive mechanism of cell survival in HER2-positive breast tumors treated with anti-HER2 therapy

Por Giuliano, Mario, Hu, Huizhong, Wang, Yen-Chao, Fu, Xiaoyong, Nardone, Agostina, Herrera, Sabrina, Mao, Sufeng, Contreras, Alejandro, Gutierrez, Carolina, Wang, Tao, Hilsenbeck, Susan G., De Angelis, Carmine, Wang, Nicholas J., Heiser, Laura M., Gray, Joe W., Lopez-Tarruella, Sara, Pavlick, Anne C., Trivedi, Meghana V., Chamness, Gary C., Chang, Jenny C., Osborne, C. Kent, Rimawi, Mothaffar F., Schiff, Rachel
Publicado no Clin Cancer Res (2015)