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Phase IB Randomized, Double-Blinded, Placebo-Controlled, Dose Escalation Study of Polyphenon E in Women with Hormone Receptor-Negative Breast Cancer

Epidemiologic data support an inverse association between green tea intake and breast cancer risk and numerous experimental studies have demonstrated the anti-tumor effects of its main component, epigallocatechin gallate (EGCG). We conducted a phase IB dose escalation trial in women with a history o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Crew, Katherine D., Brown, Powel, Greenlee, Heather, Bevers, Therese B., Arun, Banu, Hudis, Clifford, McArthur, Heather L., Chang, Jenny, Rimawi, Mothaffar, Vornik, Lana, Cornelison, Terri L., Wang, Antai, Hibshoosh, Hanina, Ahmed, Aqeel, Terry, Mary Beth, Santella, Regina M., Lippman, Scott M., Hershman, Dawn L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816771/
https://ncbi.nlm.nih.gov/pubmed/22827973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-12-0117
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