Xenografts faithfully recapitulate breast cancer-specific gene expression patterns of parent primary breast tumors

Though xenografts are used extensively for drug development in breast cancer, how well xenografts reflect the breadth of primary breast tumor subtypes has not been well characterized. Moreover, few studies have compared the gene expression of xenograft tumors to the primary tumors from which they we...

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Главные авторы: Petrillo, Laura A., Wolf, Denise M., Kapoun, Ann M., Wang, Nicholas J., Barczak, Andrea, Xiao, Yuanyuan, Korkaya, Hasan, Baehner, Frederick, Lewicki, John, Wicha, Max, Park, John W., Spellman, Paul T., Gray, Joe W., van't Veer, Laura, Esserman, Laura J.
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873871/
https://ncbi.nlm.nih.gov/pubmed/22941572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-012-2226-y
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