ARTIK-52 induces replication-dependent DNA damage and p53 activation exclusively in cells of prostate and breast cancer origin

The realization, that the androgen receptor (AR) is essential for prostate cancer (PC) even after relapse following androgen deprivation therapy motivated the search for novel types of AR inhibitors. We proposed that targeting AR expression versus its function would work in cells having either wild...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Fleyshman, Daria, Cheney, Peter, Ströse, Anda, Mudambi, Shaila, Safina, Alfiya, Commane, Mairead, Purmal, Andrei, Morgan, Kelsey, Wang, Nicholas J., Gray, Joe, Spellman, Paul T., Issaeva, Natalia, Gurova, Katerina
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4943693/
https://ncbi.nlm.nih.gov/pubmed/26694952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1127478
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