ARTIK-52 induces replication-dependent DNA damage and p53 activation exclusively in cells of prostate and breast cancer origin

The realization, that the androgen receptor (AR) is essential for prostate cancer (PC) even after relapse following androgen deprivation therapy motivated the search for novel types of AR inhibitors. We proposed that targeting AR expression versus its function would work in cells having either wild...

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Опубликовано в: :Cell Cycle
Главные авторы: Fleyshman, Daria, Cheney, Peter, Ströse, Anda, Mudambi, Shaila, Safina, Alfiya, Commane, Mairead, Purmal, Andrei, Morgan, Kelsey, Wang, Nicholas J., Gray, Joe, Spellman, Paul T., Issaeva, Natalia, Gurova, Katerina
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis 2015
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Report
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4943693/
https://ncbi.nlm.nih.gov/pubmed/26694952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1127478
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