Modular Design of Artificial Tissue Homeostasis: Robust Control through Synthetic Cellular Heterogeneity

Synthetic biology efforts have largely focused on small engineered gene networks, yet understanding how to integrate multiple synthetic modules and interface them with endogenous pathways remains a challenge. Here we present the design, system integration, and analysis of several large scale synthet...

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Detalhes bibliográficos
Principais autores: Miller, Miles, Hafner, Marc, Sontag, Eduardo, Davidsohn, Noah, Subramanian, Sairam, Purnick, Priscilla E. M., Lauffenburger, Douglas, Weiss, Ron
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400602/
https://ncbi.nlm.nih.gov/pubmed/22829755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002579
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