Modular Design of Artificial Tissue Homeostasis: Robust Control through Synthetic Cellular Heterogeneity

Synthetic biology efforts have largely focused on small engineered gene networks, yet understanding how to integrate multiple synthetic modules and interface them with endogenous pathways remains a challenge. Here we present the design, system integration, and analysis of several large scale synthet...

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Библиографические подробности
Главные авторы: Miller, Miles, Hafner, Marc, Sontag, Eduardo, Davidsohn, Noah, Subramanian, Sairam, Purnick, Priscilla E. M., Lauffenburger, Douglas, Weiss, Ron
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400602/
https://ncbi.nlm.nih.gov/pubmed/22829755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002579
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