Contribution of Regulatory-Gene Networks to Heritability of Coronary Artery Disease

BACKGROUND: Genetic variants currently known to affect coronary artery disease (CAD) risk explain less than a quarter of disease heritability. The heritability contribution of regulatory gene networks (RGNs) in CAD, which are modulated by both genetic and environmental factors, is unknown. OBJECTIVE...

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Gepubliceerd in:J Am Coll Cardiol
Hoofdauteurs: Zeng, Lingyao, Talukdar, Husain, Koplev, Simon, Giannarelli, Chiara, Ivert, Torbjörn, Gan, Li-Ming, Ruusalepp, Arno, Schadt, Eric E, Kovacic, Jason C., Lusis, Aldons J., Michoel, Tom, Schunkert, Heribert, Björkegren, Johan L.M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6590059/
https://ncbi.nlm.nih.gov/pubmed/31196451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2019.03.520
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