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Genome-Wide Significant Loci: How Important Are They?: Systems Genetics to Understand Heritability of Coronary Artery Disease and Other Common Complex Disorders
Genome-wide association studies (GWAS) have been extensively used to study common complex diseases such as coronary artery disease (CAD), revealing 153 suggestive CAD loci, of which at least 46 have been validated as having genome-wide significance. However, these loci collectively explain <10% o...
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| Publicado no: | J Am Coll Cardiol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4374657/ https://ncbi.nlm.nih.gov/pubmed/25720628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2014.12.033 |
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