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Genome-Wide Significant Loci: How Important Are They?: Systems Genetics to Understand Heritability of Coronary Artery Disease and Other Common Complex Disorders
Genome-wide association studies (GWAS) have been extensively used to study common complex diseases such as coronary artery disease (CAD), revealing 153 suggestive CAD loci, of which at least 46 have been validated as having genome-wide significance. However, these loci collectively explain <10% o...
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| Yayımlandı: | J Am Coll Cardiol |
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| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2015
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4374657/ https://ncbi.nlm.nih.gov/pubmed/25720628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2014.12.033 |
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